Highly sensitive detection of telomerase based on a DNAzyme strategy.
Highly sensitive detection of telomerase based on a DNAzyme strategy.
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DOI：
10.1039/c3cc38818b
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发表时间：
2013-03
影响因子：
4.9
通讯作者：
Tian Tian-Tian;Shuang Peng;Heng Xiao;Xiaoe Zhang;Shan Guo;Shaoru Wang;Xiang Zhou;Songmei Liu;Xin Zhou
中科院分区：
文献类型：
--
作者：
Tian Tian-Tian;Shuang Peng;Heng Xiao;Xiaoe Zhang;Shan Guo;Shaoru Wang;Xiang Zhou;Songmei Liu;Xin Zhou
本研究证明了一种测量细胞提取物中端粒酶活性的高度敏感的方法。此外，我们应用新的策略在细胞水平上原位检测癌细胞中的端粒酶，并以正常细胞作为阴性对照。
The present study demonstrated a highly sensitive strategy for measuring telomerase activity in cell extracts. Furthermore, we applied the new strategy for in situ detection of telomerase at the cellular level in cancer cells, together with a normal cell as the negative control.