Measuring depth depends on frequency in electrical skin impedance measurements
Measuring depth depends on frequency in electrical skin impedance measurements
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DOI：
10.1111/j.1600-0846.1999.tb00128.x
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发表时间：
1999-08-01
影响因子：
2.2
通讯作者：
Haug, Erlend
中科院分区：
文献类型：
--
作者：
Martinsen, Orjan G.;Grimnes, Sverre;Haug, Erlend
背景和目的：多频电测量在角质层的活体研究在文献中经常被报道。众所周知，测量的皮肤体积取决于测量频率，我们想研究活体皮肤在多大程度上影响测量的阻抗作为频率的函数。方法：使用有限元建模（FEM）来研究当用两个同心表面电极测量阻抗时皮肤中的电流和电势分布。结果：该研究表明，所测量的阻抗主要反映了低频下的角质层，在这种情况下低于1 kHz，而活性皮肤在较高频率下占主导地位。它的结论是，一个多频率的测量孤立的角质层是不可能的，在体内与传统的技术，除了在一个非常狭窄和低的频率范围内。
Backgroundaims: Multi-frequency electrical measurements in vivo on stratum corneum are frequently reported in the literature. It is well known that the measured volume of skin is dependent on measuring frequency, and we wanted to investigate to what extent viable skin influences the measured impedance as a function of frequency.Methods: Finite element modelling (FEM) was used to investigate the current and potential distribution in the skin when measuring impedance with two concentric surface electrodes.Results: The study showed that the impedance measured reflects mainly the stratum corneum at low frequencies, in this case below 1 kHz, and that the viable skin dominates at higher frequencies.Conclusion: It is concluded that a multi-frequency measurement on isolated stratum corneum is not possible in vivo with conventional techniques, except within a very narrow and low frequency range.