Comparing generic and disease-specific measures of physical and role functioning - Results from the Veterans Health Study
Comparing generic and disease-specific measures of physical and role functioning - Results from the Veterans Health Study
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DOI：
10.1097/00005650-199802000-00005
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发表时间：
1998-02-01
期刊：
影响因子：
3
通讯作者：
Rogers, W
中科院分区：
文献类型：
--
作者：
Ren, XHS;Kazis, L;Rogers, W
目标.本研究比较了医疗结果研究简表36项健康调查身体功能和角色限制的通用指标与使用慢性肺病、慢性腰痛和膝关节骨关节炎的特定疾病归因的身体功能和角色限制的疾病特异性指标的性能。方法.数据分析来自退伍军人健康研究，患者接受退伍军人管理局门诊护理。确定为患有三种研究状况之一的患者被纳入研究（n = 932）。研究显示，通用的身体功能和角色限制量表与其他通用的SF-36量表具有更高的相关性，而疾病特异性归因测量在解释基于疾病严重程度的变异性方面具有更大的R-2值，并且在区分患者服用药物和接受手术的影响方面具有更大的t统计值。身体功能和角色限制的一般措施更适用于评估广泛的健康相关的生活质量问题，而疾病特异性措施的身体功能和角色限制更有用的临床管理和限制与特定疾病条件。研究结果表明，使用特定疾病归因评估比开发新的特定疾病工具更具成本效益。疾病特异性归因可用于补充评估患者结局的一般措施。
OBJECTIVES. This study compared the performance of generic measures of Medical Outcome Study Short Form 36-Item Health Survey physical functioning and role limitations with disease-specific measures of physical functioning and role limitations using specific disease attributions for chronic lung disease, chronic low back pain, and osteoarthritis of the knee. METHODS. Data Were analyzed from the Veterans Health Study among patients receiving Veteran's Administration ambulatory care. Patients identified as having one of the three study conditions were included in the study (n = 932).RESULTS. The study revealed that the generic physical functioning and role limitations scales had higher correlations with other generic SF-36 scales, whereas disease-specific attribution measures had larger R-2 values in explaining variability in symptom-based disease severity and larger t statistic values in discriminating the impacts of patients taking medications and having surgery.CONCLUSIONS. The generic measures of physical functioning and role limitations were more applicable in assessing a broad array of health-related quality-of-life issues, whereas disease-specific measures of physical functioning and role limitations were more useful in evaluating clinical management and limitations associated with specific disease conditions. The results of the study suggest that the use of disease-specific attribution assessments was more cost-efficient than the development of new disease-specific instruments. Disease-specific attribution could be used to complement generic measures in assessing patient outcomes.