NEW CHIRAL ANISOTROPIC REAGENTS, NMR TOOLS TO ELUCIDATE THE ABSOLUTE-CONFIGURATIONS OF LONG-CHAIN ORGANIC-COMPOUNDS
NEW CHIRAL ANISOTROPIC REAGENTS, NMR TOOLS TO ELUCIDATE THE ABSOLUTE-CONFIGURATIONS OF LONG-CHAIN ORGANIC-COMPOUNDS
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DOI：
10.1016/s0040-4039(00)73366-1
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发表时间：
1994-06-20
影响因子：
1.8
通讯作者：
INOUYE, Y
中科院分区：
文献类型：
--
作者：
KUSUMI, T;TAKAHASHI, H;INOUYE, Y
用9-苯甲酰甲氧基乙酸(9ATMA)和2-萘基甲氧基萘乙酸(2NMA)代替传统方法中的mtpa，改进了Mosher法。这些试剂的各向异性效应比MTPA大得多，而且模试剂已被证明是特别有用的，特别是在确定长链化合物中所涉及的仲醇的绝对构型方面。
Modified Mosher's method has been extended by use of 9-anthranylmethoxyacetic acid (9ATMA) and 2-naphdiylmethoxynaphthylacetic acid (2NMA) instead of MTPA of the conventional method. Anisotropic effects of these reagents are much greater than that of MTPA, and die reagents have been shown to be useful especially to determine the absolute configurations of the secondary alcohols involved in long-chain compounds.