Biased hypermutagenesis associated with mutations in an untranslated hairpin of an RNA virus.
Biased hypermutagenesis associated with mutations in an untranslated hairpin of an RNA virus.
复制标题
与 RNA 病毒非翻译发夹突变相关的偏向性超突变。
DOI：
10.1128/jvi.78.14.7813-7817.2004
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Simon,AnneE
中科院分区：
文献类型：
--
作者：
McCormack,JohnC;Simon,AnneE
The mutation frequency ofTurnip crinkle viruscan increase 12-fold without inducing error catastrophe. Lesions in a hairpin repressor frequently reverted and led to second-site alterations biased for specific mutations. These results suggest that the hairpin may also function as an RNA chaperone to properly fold the RNA-dependent RNA polymerase.
