The Whole is Greater Than the Sum of Its Parts: Large-scale Phenomena Arising from Small-scale Biophysical Processes
The Whole is Greater Than the Sum of Its Parts: Large-scale Phenomena Arising from Small-scale Biophysical Processes
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整体大于部分之和：小规模生物物理过程产生的大规模现象
DOI：
10.1093/icb/icad115
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发表时间：
2023
影响因子：
2.6
通讯作者：
Chan, Kit Yu Karen
中科院分区：
文献类型：
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作者：
Wheeler, Jeanette D.;Chan, Kit Yu Karen
SICB 2023年年会的“小规模生物物理过程产生的大规模生物现象”研讨会重点关注生物学中新兴现象的跨学科探索。系统内小尺度的细胞或生物体之间的相互作用可以控制在空间、时间或生物复杂性方面发生的更大尺度的模式。这个主题在生物学的许多子学科中反复出现，包括细胞和发育生物学、进化论和生态学。本次研讨会以及此处介绍的相关特刊展示了生物学家、物理学家和工程师之间广泛的跨学科合作。显微镜和微流体技术的进步，以及数学建模和相关理论的互补进步证明了这个问题的及时性。本简介旨在提供有用的背景信息，将本问题的研究置于更广泛的生物物理学背景下，并强调跨系统和子学科的想法和方法的相似性。我们希望证明，将小规模生物物理学与更大规模的新兴现象联系起来的跨学科研究可以帮助我们理解从单细胞行为到组织形成和功能、形式进化以及群落动态等一系列问题。
The symposium “Large-scale biological phenomena arising from small-scale biophysical processes” at the SICB 2023 Annual General Meeting focused on the cross-disciplinary exploration of emergent phenomena in biology. Interactions between cells or organisms at small scales within a system can govern patterns occurring at larger scales in space, time, or biological complexity. This theme recurs in many sub-disciplines of biology, including cell and developmental biology, evolution, and ecology. This symposium, and the associated special issue introduced here, showcases a wide range of cross-disciplinary collaborations among biologists, physicists, and engineers. Technological advancements in microscopy and microfluidics, as well as complementary advances in mathematical modeling and associated theory demonstrate the timeliness of this issue. This introduction seeks to provide useful background information to place the studies within this issue in a broader biophysical context and highlight similarities in ideas and approaches across systems and sub-disciplines. We hope to demonstrate that cross-disciplinary research linking small-scale biophysics to larger-scale emergent phenomena can help us understand problems ranging from single-cell behaviors to tissue formation and function, evolution of form, and the dynamics of communities.