Computational Fluid Dynamics Turbulence Model and Experimental Study for a Fontan Cavopulmonary Assist Device.
Computational Fluid Dynamics Turbulence Model and Experimental Study for a Fontan Cavopulmonary Assist Device.
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Fontan Cavopulmonary 辅助装置的计算流体动力学湍流模型和实验研究。
DOI：
10.1115/1.4063088
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发表时间：
2023
期刊：
影响因子：
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通讯作者：
Ivashchenko,Artem
中科院分区：
文献类型：
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作者：
Sarfare,Shreyas;Ali,MdShujan;Palazzolo,Alan;Rodefeld,Mark;Conover,Tim;Figliola,Richard;Giridharan,Guruprasad;Wampler,Richard;Bennett,Edward;Ivashchenko,Artem
使用模拟循环回路中的血液替代物测量Fontan腔静脉辅助装置（CPAD）的头流HQ曲线，并使用各种计算流体动力学（CFD）模型进行模拟。这些测试为进一步增强CPAD设计的CFD工具提供了基准。当应用于Fontan CPAD时，发现推荐的用于开发传统心室辅助装置（VAD）的雷诺平均纳维-斯托克斯（RANS）CFD方法存在缺陷，Fontan CPAD旨在消除可能导致重大不良事件的非正常阻塞风险。无阻塞条件是通过冯卡门泵实现的，利用大间隙和小叶片高度，这挑战了传统的VAD基于RANS的CFD血液动力学模拟。高保真大涡模拟（LES）始终是推荐的;然而，这可能是在商业环境中的优化研究的成本过高，因此依赖于RANS模型。本研究比较了各种RANS湍流模型的头和功率预测，采用实验测量和LES结果作为比较的基础。这些模式包括标准模式、再规范化模式、可实现模式、剪切应力输送模式、有转捩湍流的SST模式和广义模式。对于压头的预测，据观察，standardmodel提供了更好的协议与实验。对于转子扭矩，预测值比LES低30%，而SST和LES扭矩值几乎相同。对于Fontan CPAD，研究结果支持使用LES进行最终设计模拟，使用模型进行头部和一般流量模拟，使用SST进行功率、剪切应力、溶血和血栓形成预测。
Head-flow HQ curves for a Fontan cavopulmonary assist device (CPAD) were measured using a blood surrogate in a mock circulatory loop and simulated with various computational fluid dynamics (CFD) models. The tests benchmarked the CFD tools for further enhancement of the CPAD design. Recommended Reynolds-Averaged Navier–Stokes (RANS) CFD approaches for the development of conventional ventricular assist devices (VAD) were found to have shortcomings when applied to the Fontan CPAD, which is designed to neutralize off-condition obstruction risks that could contribute to a major adverse event. The no-obstruction condition is achieved with a von Karman pump, utilizing large clearances and small blade heights, which challenge conventional VAD RANS-based CFD hemodynamic simulations. High-fidelity large eddy simulation (LES) is always recommended; however, this may be cost-inhibitive for optimization studies in commercial settings, thus the reliance on RANS models. This study compares head and power predictions of various RANS turbulence models, employing experimental measurements and LES results as a basis for comparison. The models include standard, re-normalization group, realizable, shear stress transport (SST), SST with transitional turbulence, and Generalized. For the pressure head predictions, it was observed that the standardmodel provided far better agreement with experiment. For the rotor torque,predictions were 30% lower than LES, while the SST and LES torque values were near identical. For the Fontan CPAD, the findings support using LES for the final design simulations,model for head and general flow simulation, and SST for power, shear stress, hemolysis, and thrombogenicity predictions.