Reproductive maturation, somatic growth and testosterone among Zimbabwe boys
Reproductive maturation, somatic growth and testosterone among Zimbabwe boys
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DOI：
10.1080/03014460500424068
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发表时间：
2006-01-01
影响因子：
1.7
通讯作者：
Mbizo, M
中科院分区：
文献类型：
--
作者：
Campbell, B;Mbizo, M
背景：关于精力状态在男性青春期发育中的作用，人们知之甚少。目的：确定撒哈拉以南人口中睾酮的产生和生物利用度与能量状态和躯体生长的关系。对象和方法：采集来自哈拉雷地区4所高中的441名12-18岁津巴布韦男生的人体测量、第二性征、血斑和唾液样本。结果：唾液和血睾酮在14至15岁之间首次显著增加。在控制Tanner生殖器阶段和年龄后，唾液和血液中的睾酮均与肩胛骨下皮褶厚度呈正相关，但与三头肌皮褶厚度无关。控制了Tanner生殖器阶段和年龄，唾液而不是血液中的睾酮与髂上皮皱有关。血睾酮，而不是唾液睾酮，显示出与坦纳生殖器阶段有显著关系，控制了年龄和眉上皮褶。血液和唾液睾酮与身高、上臂肌肉和骨骼面积的关系相似。结论：这些结果支持了男性青春期能量状态，特别是腹部脂肪对睾酮生物利用度的影响的假说。然而，他们未能证明生物可利用的睾丸素对身体生长的明显影响。
Background: Little is known about the role of energetic status in the timing of puberty among males across populations.Aim: To determine the relationship of testosterone production and bioavailability to energetic status and somatic growth in a sub-Saharan population.Subjects and methods: Anthropometric measures, secondary sexual characteristics, blood spot and salivary samples were obtained from 441 Zimbabwe school boys, aged 12 - 18, from four high schools in the Harare area.Results: Salivary and blood testosterone both showed their first significant increase between 14 and 15 years of age. Both salivary and blood testosterone were positively related to subscapular, but not triceps skinfold, when controlled for Tanner genital stage and age. Controlled for Tanner genital stage and age, salivary, but not blood testosterone was related to suprailiac skinfolds. Blood testosterone, but not salivary testosterone, showed a significant relationship with Tanner genital stage, controlled for age and suprailic skinfolds. Blood and salivary testosterone showed similar relationships with height and arm muscle plus bone area.Conclusion: These results provide support for the hypothesis that energetic status, especially abdominal fat plays a role in bioavailable testosterone during male puberty. However, they fail to demonstrate a clear effect of bioavailable testosterone on somatic growth.