The orbitofrontal cortex and the computation of subjective value: consolidated concepts and new perspectives
The orbitofrontal cortex and the computation of subjective value: consolidated concepts and new perspectives
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DOI：
10.1111/j.1749-6632.2011.06262.x
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发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Cai, Xinying
中科院分区：
文献类型：
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作者：
Padoa-Schioppa, Camillo;Cai, Xinying
近年来，在了解眶前叶皮质(OFC)的功能方面取得了显着进展。许多使用灵长类神经生理学和人类成像的研究证实并推广了这一发现，即这一区域的神经元编码猴子在做出选择时分配给不同商品的主观价值。此外，新的损伤研究表明，在OFC中计算的主观价值与选择行为有因果关系，并与选择行为具体相关。重要的是，OFC的价值依附于商品，而不是行动或空间位置。此外，主观价值似乎是在这一领域计算出来的，即使情况不需要选择。鉴于这一不断增长的工作主体，我们建议OFC的主要功能是在抽象表示中计算良好的同一性和主观值。在这个观点中，OFC神经元计算出当一种商品与行为相关时该商品的主观价值。
Remarkable progress has been made in recent years toward understanding the functions of the orbitofrontal cortex (OFC). The finding that neurons in this area encode the subjective value monkeys assign to different goods while making choices has been confirmed and extended by numerous studies using both primate neurophysiology and human imaging. Moreover, new lesion studies demonstrated that subjective values computed in the OFC are causally and specifically related to choice behavior. Importantly, values in the OFC are attached to goods, not to actions or to spatial locations. Furthermore, subjective values appear to be computed in this area even if the situation does not require a choice. In the light of this growing body of work, we propose that the primary function of the OFC is the computation of good identities and subjective values in an abstract representation. In this view, OFC neurons compute the subjective value of a good whenever that good is behaviorally relevant.