A timeline of pharyngeal endoskeletal condensation and differentiation in the shark, Scyliorhinus canicula, and the paddlefish, Polyodon spathula.
A timeline of pharyngeal endoskeletal condensation and differentiation in the shark, Scyliorhinus canicula, and the paddlefish, Polyodon spathula.
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DOI：
10.1111/j.1439-0426.2012.01976.x
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发表时间：
2012-06-01
期刊：
影响因子：
--
通讯作者：
Baker CVH
中科院分区：
文献类型：
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作者：
Gillis JA;Modrell MS;Baker CVH
小斑星鲨（Scyliorhinus canicula）和北美匙吻鲟（Polyodon spathula）是研究脊椎动物颅面发育的两个新兴模式系统。值得注意的是，相对于更常用的脊椎动物颅面发育模型（例如斑马鱼、鸡和小鼠），这两个类群都保留了咽内骨骼组织的原始特征，因此非常适合用于了解有颌脊椎动物最后共同祖先中起作用的咽内骨骼模式形成机制。在此，我们对颌、舌骨和鳃弓最显著的内骨骼元件——分别为腭方软骨/ Meckel软骨、舌颌骨/角舌骨以及上鳃/角鳃软骨——在小斑星鲨和北美匙吻鲟胚胎系列中的凝聚和软骨形成进行了组织学概述。我们的观察结果为在这些具有系统发育信息的类群中进一步开展咽内骨骼分化和模式形成的分子发育及功能研究提供了一个临时的时间线和解剖学框架。
The lesser-spotted dogfish (Scyliorhinus canicula) and the North American paddlefish (Polyodon spathula) are two emerging model systems for the study of vertebrate craniofacial development. Notably, both of these taxa have retained plesiomorphic aspects of pharyngeal endoskeletal organization, relative to more commonly used models of vertebrate craniofacial development (e.g. zebrafish, chick and mouse), and are therefore well suited to inform the pharyngeal endoskeletal patterning mechanisms that functioned in the last common ancestor of jawed vertebrates. Here, we present a histological overview of the condensation and chondrogenesis of the most prominent endoskeletal elements of the jaw, hyoid and gill arches – the palatoquadrate/Meckel’s cartilage, the hyomandibula/ceratohyal, and the epi-/ceratobranchial cartilages, respectively – in embryonic series of S. canicula and P. spathula. Our observations provide a provisional timeline and anatomical framework for further molecular developmental and functional investigations of pharyngeal endoskeletal differentiation and patterning in these phylogenetically informative taxa.