Epidemiology, diagnosis and control of classical swine fever: Recent developments and future challenges
Epidemiology, diagnosis and control of classical swine fever: Recent developments and future challenges
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DOI：
10.1111/tbed.12676
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发表时间：
2018-05-01
影响因子：
4.3
通讯作者：
Becher, Paul
中科院分区：
文献类型：
--
作者：
Postel, Alexander;Austermann-Busch, Sophia;Becher, Paul
猪瘟（CSF）是养猪业的一个主要健康和贸易问题。在流行国家或有野猪水库的国家，CSF仍然是兽医服务的优先事项。监测以及消灭和/或接种疫苗是预防和控制的主要工具，视情况而定。在过去的几十年中，已经开发出了标记疫苗和伴随的诊断测试，可以区分感染的动物和接种疫苗的动物。在欧盟，E2亚单位和嵌合活疫苗已获得许可，可用于未来疾病爆发的情况。实施普遍接受和全球统一的概念可以为用活疫苗战略取代道德上有问题的淘汰政策铺平道路，从而避免扑杀大量健康动物并节省粮食资源。虽然世界各地都有一些疫苗和诊断测试，但这两个领域的技术进步是可取的。这项工作提供了一个由DISCONTOOLS专家组进行的CSF分析摘要。
Classical swine fever (CSF) represents a major health and trade problem for the pig industry. In endemic countries or those with a wild boar reservoir, CSF remains a priority for Veterinary Services. Surveillance as well as stamping out and/or vaccination are the principle tools of prevention and control, depending on the context. In the past decades, marker vaccines and accompanying diagnostic tests allowing the discrimination of infected from vaccinated animals have been developed. In the European Union, an E2 subunit and a chimeric live vaccine have been licensed and are available for the use in future disease outbreak scenarios. The implementation of commonly accepted and globally harmonized concepts could pave the way to replace the ethically questionable stamping out policy by a vaccination-to-live strategy and thereby avoid culling of a large number of healthy animals and save food resources. Although a number of vaccines and diagnostic tests are available worldwide, technological advancement in both domains is desirable. This work provides a summary of an analysis undertaken by the DISCONTOOLS group of experts on CSF.