Mediterranean and Dietary Approaches to Stop Hypertension dietary patterns and risk of sudden cardiac death in postmenopausal women
Mediterranean and Dietary Approaches to Stop Hypertension dietary patterns and risk of sudden cardiac death in postmenopausal women
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DOI：
10.3945/ajcn.112.056135
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发表时间：
2014-02-01
影响因子：
7.1
通讯作者：
Eaton, Charles B.
中科院分区：
文献类型：
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作者：
Bertoia, Monica L.;Triche, Elizabeth W.;Eaton, Charles B.
背景资料：地中海和饮食方法阻止高血压（DASH）饮食的特点是水果，蔬菜，全谷物和不饱和脂肪酸的摄入量较高。所有这些食物和营养素可能会影响胆固醇、炎症、动脉粥样硬化的发展，因此，心脏性死亡的风险。目的：我们的目的是研究地中海和DASH饮食模式与女性心脏性猝死（SCD）风险之间的关系。设计：我们使用了一个前瞻性队列，93,122名绝经后妇女在1993年至1998年期间参加了妇女健康倡议研究，平均随访10.5年。在随访期间，女性完成了两次食物频率问卷（FFQ）。我们根据报告的饮食与每种饮食模式的相似程度对他们的饮食进行评分。SCD被定义为死亡，发生在1小时内症状onset.Results：较高的地中海饮食评分与较低的SCD风险（FIR：0.64; 95%CI：0.43，0.94）时，妇女在最高的五分之一与妇女在最低的五分之一调整后的年龄，总能量，种族，收入，吸烟，体力活动。调整潜在介质后，相关性相似（HR：0.67; 95% CI：0.46，0.99）。较高的DASH饮食评分与SCD风险无关。然而，钠的摄入量，这是一个重要组成部分的DASH饮食模式，没有得到很好的特点FFQ.Conclusion：地中海饮食模式可能与女性SCD的风险较低。
Background: The Mediterranean and Dietary Approaches to Stop Hypertension (DASH) diets are characterized by higher intake of fruit, vegetables, whole grains, and unsaturated fatty acids. All of these foods and nutrients may affect cholesterol, inflammation, the development of atherosclerosis, and, therefore, risk of cardiac death.Objective: Our objective was to examine the association between the Mediterranean and DASH dietary patterns and risk of sudden cardiac death (SCD) in women.Design: We used a prospective cohort of 93,122 postmenopausal women enrolled in the Women's Health Initiative study between 1993 and 1998 and followed for an average of 10.5 y. Women completed a food-frequency questionnaire (FFQ) twice during follow-up. We scored their diets according to how closely the reported diet resembled each dietary pattern. SCD was defined as death that occurred within 1 h of symptom onset.Results: A higher Mediterranean diet score was associated with lower risk of SCD (FIR: 0.64; 95% CI: 0.43, 0.94) when women in the highest quintile were compared with women in the lowest quintile after adjustment for age, total energy, race, income, smoking, and physical activity. After adjustment for potential mediators, the association was similar (HR: 0.67; 95% CI: 0.46, 0.99). A higher DASH diet score was not associated with risk of SCD. However, sodium intake, which is a crucial component of the DASH dietary pattern, was not well characterized by the FFQ.Conclusion: The Mediterranean dietary pattern may be associated with lower risk of SCD in women.