Time-linked concurrence of sleep bruxism, periodic limb movements, and EEG arousals in sleep bruxers and healthy controls
Time-linked concurrence of sleep bruxism, periodic limb movements, and EEG arousals in sleep bruxers and healthy controls
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磨牙症患者和健康对照者中睡眠磨牙症、周期性肢体运动和脑电图唤醒的时间相关性
DOI：
10.1007/s00784-013-0994-3
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发表时间：
2013
影响因子：
3.4
通讯作者：
F. Lobbezoo
中科院分区：
文献类型：
--
作者：
J. Zaag;M. Naeije;D. J. Wicks;H. Hamburger;F. Lobbezoo
目的睡眠磨牙症（SB）和睡眠期间周期性肢体运动（PLMS）可能有共同的神经生理机制，特别是与睡眠相关的脑电（EEG）觉醒的发生有关。为了验证这一假设，我们对三个研究问题进行了评估。首先，它是评估是否PLMS事件发生更频繁的SB患者比个人没有SB。第二，提出的问题是否SB和PLMS事件的组合存在是更常见的比孤立的SB或PLMS事件在一组SB患者。第三，为了进一步阐明EEG觉醒在SB和PLMS的潜在神经生理机制中的可能作用，在一组SB患者中评估了具有相关EEG觉醒的组合SB/PLMS事件是否比没有相关EEG觉醒的那些更常见。这些问题的积极答案可能会建议一个共同的神经生理学基础的运动disorders.Materials和MethodsSeventeen SB患者和11名健康对照进行了多导睡眠图研究。对SB、PLMS和EEG唤醒进行评分。结果SB患者PLMS指数高于健康对照组（P < 0.001）。在SB患者组中，合并SB/PLMS指数高于单独SB指数（P < 0.001）和单独PLMS指数（P = 0.018）。结论SB、PLMS和EEG觉醒在睡眠中存在时间相关性，SB和PLMS可能有共同的神经生理机制。
ObjectiveSleep bruxism (SB) and periodic limb movements during sleep (PLMS) may have a common underlying neurophysiologic mechanism, especially in relation to the occurrence of sleep-related electroencephalographic (EEG) arousals. To test this hypothesis, three research questions were assessed. First, it was assessed whether PLMS events occur more frequently in SB patients than in individuals without SB. Second, the question was put forward whether the combined presence of SB and PLMS events is more common than that of isolated SB or PLMS events in a group of SB patients. Third, as to further unravel the possible role of EEG arousals in the underlying neurophysiologic mechanism of SB and PLMS, it was assessed in a group of SB patients whether combined SB/PLMS events with associated EEG arousals are more common than those without associated EEG arousals. Positive answers to these questions could suggest a common neurophysiological basis for both movement disorders.Materials and methodsSeventeen SB patients and 11 healthy controls were polysomnographically studied. SB, PLMS, and EEG arousals were scored. An association was noted when the occurrence was within a 3-s association zone.ResultsThe PLMS index was higher in SB patients than in healthy controls (P < 0.001). Within the group of SB patients, the combined SB/PLMS index was higher than the isolated SB index (P < 0.001) and the isolated PLMS index (P = 0.018). Similarly, the combined SB/PLMS index with EEG arousal was higher than the combined SB/PLMS index without EEG arousal in SB patients (P < 0.001).ConclusionThe results of this study indicate that SB, PLMS, and EEG arousals commonly concur during sleep in a time-linked manner.Clinical relevanceSB and PLMS probably have a common underlying neurophysiological mechanism.
DOI：
--
发表时间：
1992
期刊：
Journal of craniomandibular disorders : facial & oral pain
影响因子：
--
作者：
S. Dworkin;L. Leresche
通讯作者：
S. Dworkin;L. Leresche