Breast implants: the good, the bad and the ugly. Can nanotechnology improve implants?
Breast implants: the good, the bad and the ugly. Can nanotechnology improve implants?
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DOI：
10.1002/wnan.164
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发表时间：
2012-03
期刊：
影响因子：
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通讯作者：
J. Puskas;Matthew T. Luebbers
中科院分区：
文献类型：
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作者：
J. Puskas;Matthew T. Luebbers
这篇高级综述将讨论乳房重建和隆乳中使用的植入物的历史，这是当今最常见的整形手术。目前，只有硅橡胶基二氧化硅纳米复合材料植入物在美国可用。涉及乳房植入体的最常见问题包括包囊挛缩、凝胶出血、植入体破裂和感染。在过去，也有研究报告称，乳房植入体与全身性疾病的发病率增加有关，如自身免疫性疾病，各种形式的癌症和心理疾病。这篇综述的目的是从材料科学的角度对文献进行综述。纳米技术也很大程度上没有被注意到：硅橡胶外壳用纳米二氧化硅加固，因此植入物看起来均匀而透明。我们希望这篇评论将有助于更好地理解有争议的问题，并激励材料科学家和医生共同努力，为选择合成材料制成的设备的女性开发基于新纳米技术的替代品。
This advanced review will discuss the history of implants used in breast reconstruction and augmentation, the most frequently performed plastic surgery today. Currently, only silicone rubber-based silica nanocomposite implants are available in the United States. The most prevalent issues involving breast implants include capsular contracture, gel bleed, implant rupture, and infection. In the past, studies have also been reported which linked breast implants to increased incidence of systemic diseases such as autoimmune disease, various forms of cancer, and psychological disease. The goal of this review is to survey the literature from the perspective of material science. It is also largely unnoticed that nanotechnology is involved: the silicone rubber shell is reinforced with nanosilica so implants appear to be homogeneous and crystal clear. We are hoping that this review will contribute to a better understanding of the controversial issues and motivate material scientists and medical doctors to work together to develop alternatives based on new nanotechnology for the women who opt for a device made of synthetic materials.