Myoglobin as a new fluorescence probe to sense H2S.
Myoglobin as a new fluorescence probe to sense H2S.
复制标题
DOI：
10.2174/092986611794578378
复制
发表时间：
2011-02
影响因子：
1.6
通讯作者：
M. Strianese;F. De Martino;C. Pellecchia;G. Ruggiero;S. d'Auria
中科院分区：
文献类型：
--
作者：
M. Strianese;F. De Martino;C. Pellecchia;G. Ruggiero;S. d'Auria
研制了一种新型、快速、简单、经济的硫化氢监测传感装置。报道了一种廉价的肌红蛋白（Mb）作为荧光生物传感器的生物探针用于检测硫化氢的原理性验证结果。本研究选择了两种不同的商业标签Cy3和Atto620。该传感系统不仅在溶液中，而且在固态器件中也有很好的应用前景。
A new, fast, simple and cost-effective sensing device for monitoring H(2)S has been developed. Proof-of-principle results showing that a commercial and cheap Myoglobin (Mb) can be successfully used as a biological probe for a fluorescence biosensor for H(2)S detection are reported. The two different commercial labels Cy3 and Atto620 were selected for this study. A high selectivity for detecting H(2)S against other thiols was found. The applicability of the proposed sensing system was successfully explored not only in solution but also when applied in the form of a solid state device.