A thermal monitoring sheet with low influence from adjacent waterbolus for tissue surface thermometry during clinical hyperthermia.
A thermal monitoring sheet with low influence from adjacent waterbolus for tissue surface thermometry during clinical hyperthermia.
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DOI：
10.1109/tbme.2008.925693
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发表时间：
2008-10
期刊：
影响因子：
--
通讯作者：
Stauffer PR
中科院分区：
文献类型：
--
作者：
Arunachalam K;Maccarini PF;Stauffer PR
本文介绍了一种新的适形表面温度计的设计与方向灵敏度的真实的时间温度监测在高温治疗的大型浅表性癌症的完整的热分析。本文讨论的热监测片（TMS）由嵌入在两层柔性、低损耗和导热印刷电路板（PCB）薄膜之间的二维光纤传感器阵列组成。使用3D热模拟软件研究了从组织表面通过围绕小型埋入式温度传感器的多层绝缘层并进入相邻温度调节水耦合团的所有界面的热传递。进行了理论分析，以确定最有效的差分TMS探头配置可能与市售的柔性PCB材料，并比较其热响应与全向探头常用的临床热疗。提出了采用0.0508 m Kapton MTB®和0.2032 mm Kapton HN®柔性聚酰亚胺膜的TMS传感器设计，用于组织表面温度测量，其中相邻水团的影响较小。热模拟与临床探头的比较表明，新的差分TMS探头设计在选择性阅读组织表面温度的瞬态响应和稳态精度方面优于其他探头，同时降低了耦合水团和组织表面之间探头的整体热屏障。
This paper presents a complete thermal analysis of a novel conformal surface thermometer design with directional sensitivity for real time temperature monitoring during hyperthermia treatments of large superficial cancer. The thermal monitoring sheet (TMS) discussed in this paper consists of a two-dimensional array of fiberoptic sensors embedded between two layers of flexible, low loss and thermally conductive printed circuit board (PCB) film. Heat transfer across all interfaces from the tissue surface through multiple layers of insulating dielectrics surrounding the small buried temperature sensor and into an adjacent temperature regulated water coupling bolus was studied using 3D thermal simulation software. Theoretical analyses were carried out to identify the most effective differential TMS probe configuration possible with commercially available flexible PCB materials, and to compare their thermal responses with omni-directional probes commonly used in clinical hyperthermia. A TMS sensor design that employs 0.0508m Kapton MTB® and 0.2032 mm Kapton HN® flexible polyimide films is proposed for tissue surface thermometry with low influence from the adjacent waterbolus. Comparison of the thermal simulations with clinical probes indicate the new differential TMS probe design to outperform in terms of both transient response and steady state accuracy in selectively reading the tissue surface temperature, while decreasing the overall thermal barrier of the probe between the coupling waterbolus and tissue surface.