Diffuse pulmonary hamartoma: a case report
Diffuse pulmonary hamartoma: a case report
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DOI：
10.1016/j.prp.2004.09.009
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发表时间：
2005-01-01
影响因子：
2.8
通讯作者：
Noguchi, M
中科院分区：
文献类型：
--
作者：
Minami, Y;Iijima, T;Noguchi, M
肺错构瘤通常是一个良性的，边界清楚的肺实质内的单个结节。我们报告一个独特的病例，错构瘤沿着支气管树延伸沿着，形成支气管内息肉样病变，并扩展到肺实质。患者为48岁男性，因呼吸困难和胸痛入院。对组织学诊断为错构瘤的肿瘤病变进行了经支气管活检。由于发现病变沿支气管树沿着扩散生长，因此进行了左肺切除术。大体检查显示，黄色软组织已包围支气管树并延伸至肺实质。组织学上，病变主要包含成熟的脂肪组织、软骨和肌肉组织，在粘液瘤基质中含有少量短梭形细胞。患者被诊断为弥漫性肺错构瘤。(c)2004年Elsevier GmbH。All rights reserved.
Pulmonary hamartoma usually occurs as a benign, well-circumscribed single nodule in the lung parenchyma. We report on a unique case of hamartoma that extended along the bronchial tree, formed endobronchial polypoid lesions, and expanded into the lung parenchyma. The patient, a 48-year-old man, was admitted with dyspnea and chest pain. A transbronchial biopsy was performed on a tumorous lesion that was diagnosed histologically as a hamartoma. As this lesion was found to be growing diffusely along the bronchial tree, a left pneumonectomy was performed. Gross examination showed that yellowish soft tissue had surrounded the bronchial tree and extended into the lung parenchyma. Histologically, the lesion contained mainly mature adipose tissue, cartilage, and muscle tissue with a minor component of short spindle cells in a myxomatous matrix. The patient was diagnosed as having diffuse pulmonary hamartoma. (c) 2004 Elsevier GmbH. All rights reserved.