Factors regulating ovarian function in pigs
Factors regulating ovarian function in pigs
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DOI：
10.1016/j.domaniend.2005.02.030
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发表时间：
2005-08-01
影响因子：
2.1
通讯作者：
Einarsson, S
中科院分区：
文献类型：
--
作者：
Madej, A;Lang, A;Einarsson, S
下丘脑-垂体-卵巢-子宫轴的激素相互作用是母猪正常繁殖的原因。了解排卵期的发情症状和激素水平是很重要的。经直肠超声检查在母猪中的引入使我们有可能研究清醒动物的卵巢活动，并将发情时间与排卵联系起来。将该技术与几种激素如促黄体激素（LH）、促卵泡激素（FSH）、雌二醇、孕酮、胰岛素样生长激素I（IGF-I）、前列腺素F2（PGF 2）的测量相结合。代谢产物催产素有助于我们了解卵巢事件的顺序。有证据表明，下丘脑-垂体-肾上腺轴的激活可能会阻碍正常的促性腺激素分泌，从而影响卵巢功能。哺乳期代谢状况、仔猪断奶和社会应激可能影响卵巢活动的启动及相关的发情行为。精浆的作用，人工授精和公猪的存在也可能包括作为调节排卵的时间动力学，黄体发育，子宫功能和卵巢类固醇产生的因素。通过促肾上腺皮质激素（ACTH）给药或禁食模拟应激的研究是了解卵巢如何易受损伤的工具。本文的目的是审查目前的知识有关的内分泌方面的正常和应激影响卵巢功能的猪。(c)2005年爱思唯尔公司All rights reserved.
The hormonal interactions of the hypothalamic-pituitary-ovarian-uterine axis are accountable for a normal reproduction in female pigs. It is of importance to have knowledge of estrous symptoms and hormonal profiles around ovulation. The introduction of the transrectal ultrasonography in sows has given us the possibility to study ovarian activity in conscious animals and relate the timing of estrus to ovulation. Combining this technique with measuring of several hormones like luteinizing hormone (LH), follicle-stimulating hormone (FSH), inhibin, estradiol, progesterone, insulin-like growth hormone I (IGF-I), prostaglandin F2, (PGF2.) metabolite, oxytocin, facilitate our knowledge about the sequence of ovarian events. Evidence suggests that activation of the hypothalamic-pituitary-adrenal axis may hamper the normal gonadotropin secretion and in consequence, the ovarian function. The metabolic status during lactation, weaning of piglets and social stress might affect onset of ovarian activity and the related estrous behavior. The role of seminal plasma, artificial insemination and presence of the boar might also be included as factors regulating the temporal kinetics of ovulation, corpus luteum development, uterine function and steroid production in the ovary. Studies using a simulated stress by means of adrenocorticotrophic hormone (ACTH) administration or food deprivation are tools in understanding how the ovary is susceptible to impairment. The intention of this paper is to review current knowledge concerning the endocrine aspects of normal and stress-influenced ovarian function in pigs. (c) 2005 Elsevier Inc. All rights reserved.