Biologically Active 2-oxazolidinone Derivatives beyond Antibacterial Activities
Biologically Active 2-oxazolidinone Derivatives beyond Antibacterial Activities
复制标题
具有抗菌活性的生物活性 2-恶唑烷酮衍生物
DOI：
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发表时间：
2022
影响因子：
4.1
通讯作者：
Siyuan Chen
中科院分区：
文献类型：
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作者：
Leer Yuan;Rong Sheng;Mengying Guan;Yuan Wang;Siyuan Chen
摘要：2-恶唑烷酮是市面上以利奈唑胺和泰地唑胺为代表的抗菌药物的药效团。另一方面，关于2-恶唑烷酮类化合物除抗菌活性外的各种生物活性的报道也越来越多。因此，本文综述了近10年来（2011-2021年）2-恶唑烷酮这一非传统领域的研究进展。
Abstract: 2-oxazolidinone is well known as a pharmacophore for antibacterial agents represented by two marketed medicines, Linezolid and Tedizolid. On the other hand, there are growing reports on the various biological activities of 2-oxazolidinones beyond antibacterial activities. Therefore, in this review, we provide an overview of the progress of this untraditional area of 2-oxazolidinones in the past 10 years (2011-2021).