BDNF A196G and C270T gene polymorphisms and susceptibility to multiple sclerosis in the polish population.: Gender differences
BDNF A196G and C270T gene polymorphisms and susceptibility to multiple sclerosis in the polish population.: Gender differences
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DOI：
10.1016/j.jneuroim.2007.10.013
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发表时间：
2008-01-01
影响因子：
3.3
通讯作者：
Czlonkowska, Anna
中科院分区：
文献类型：
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作者：
Mirowska-Guzel, Dagmara;Mach, Anna;Czlonkowska, Anna
两个单核苷酸多态性的人BDNF基因，G196 A和C270 T，以及它们对MS的易感性和疾病进展的波兰人口进行了调查。196 G/G携带者（OR - 1.63，p=0.01）（仅女性）和270 C/T携带者（OR - 7.76，p
Two single nucleotide polymorphisms of the human BDNF gene, G196A and C270T, and their impact on the susceptibility to MS and disease progression in the Polish population were investigated. Increased risk of the disease was found for 196G/G carriers (OR - 1.63, p=0.01) (only females) and 270C/T carriers (OR - 7.76, p