Jaws-only IMRT using direct aperture optimization
Jaws-only IMRT using direct aperture optimization
复制标题
DOI：
10.1118/1.2403966
复制
发表时间：
2007-01-01
期刊：
影响因子：
3.8
通讯作者：
Shepard, D. M.
中科院分区：
文献类型：
--
作者：
Earl, M. A.;Afghan, M. K. N.;Shepard, D. M.
使用直接孔径优化，我们已经开发出一种逆向规划方法，能够产生有效的调强放射治疗（IMRT）治疗计划，可以提供没有多叶准直器。IMRT的这种“仅颌部”方法使用一系列矩形场形状来实现来自每个射束方向的高度强度调制。直接孔径优化用于直接优化钳口位置和分配给每个孔径的相对权重。因为由夹爪施加的约束被并入优化中，所以消除了对叶排序的需要。结果显示了5例患者病例，涵盖3个治疗部位：胰腺、乳腺和前列腺。对于这些情况，每个射束方向需要15至20个仅颌部孔径，以获得适形IMRT治疗计划。将每个计划输送到体模，并记录绝对和相对剂量测量值。提供这些计划的典型治疗时间为18分钟。仅颌部方法为没有多叶准直器的诊所提供了额外的IMRT输送选项。(c)2007年美国医学物理学家协会。
Using direct aperture optimization, we have developed an inverse planning approach that is capable of producing efficient intensity modulated radiotherapy (IMRT) treatment plans that can be delivered without a multileaf collimator. This "jaws-only" approach to IMRT uses a series of rectangular field shapes to achieve a high degree of intensity modulation from each beam direction. Direct aperture optimization is used to directly optimize the jaw positions and the relative weights assigned to each aperture. Because the constraints imposed by the jaws are incorporated into the optimization, the need for leaf sequencing is eliminated. Results are shown for five patient cases covering three treatment sites: pancreas, breast, and prostate. For these cases, between 15 and 20 jaws-only apertures were required per beam direction in order to obtain conformal IMRT treatment plans. Each plan was delivered to a phantom, and absolute and relative dose measurements were recorded. The typical treatment time to deliver these plans was 18 min. The jaws-only approach provides an additional IMRT delivery option for clinics without a multileaf collimator. (c) 2007 American Association of Physicists in Medicine.