Ebola Virus Disease Complications as Experienced by Survivors in Sierra Leone.
Ebola Virus Disease Complications as Experienced by Survivors in Sierra Leone.
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DOI：
10.1093/cid/ciw158
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发表时间：
2016-06-01
期刊：
影响因子：
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通讯作者：
Ciglenecki I
中科院分区：
文献类型：
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作者：
Tiffany A;Vetter P;Mattia J;Dayer JA;Bartsch M;Kasztura M;Sterk E;Tijerino AM;Kaiser L;Ciglenecki I
在我们的诊所，埃博拉病毒病（EVD）幸存者经历的主要并发症是关节痛和葡萄膜炎，如前所述。EVD并发症的治疗应是系统的，并尽快开始，以防止严重残疾，如失明。背景：在埃博拉病毒病（EVD）持续爆发期间，数千人幸存下来。 然而，关于长期EVD后并发症的频率和风险因素的数据仍然很少。我们描述了在塞拉利昂弗里敦幸存者诊所随访的EVD幸存者的临床特征。方法：在塞拉利昂弗里敦的埃博拉治疗中心内开设了一家幸存者诊所。 每次访问时，都进行临床和心理评估，并提供免费治疗。如果幸存者的病情无法在诊所得到控制，他们将被转诊到伙伴医院。我们使用从临床常规收集的数据来描述EVD的长期并发症及其风险因素。结果：2015年2月3日至6月21日期间，共为166名患者提供了1001次医疗咨询。 最常见的投诉和诊断是关节痛（n = 129 [77.7%]），疲乏（n = 116 [69.8%]），腹痛（n = 90 [54.2%]）、头痛（n = 87 [52.4%]）、贫血（n = 83 [50%]）、皮肤病（n = 81 [48.8%]）、背痛（n = 54 [32.5%]）和脱发（n = 53 [31.9%]）。在94名幸存者（56.7%）中诊断出眼部并发症;葡萄膜炎是最常见的（n = 57 [34%]）。如果存活者在其疾病的急性期出现红眼/充血眼，则EVD后发生葡萄膜炎的可能性增加10倍。结论：我们的患者中EVD后并发症与先前描述的相似，并且在疾病急性期后早期发现。 出院后应立即开始对幸存者进行随访，以解决后遗症，并减少失明等长期残疾的可能性。
The main complications experienced by Ebola virus disease (EVD) survivors in our clinic were arthralgia and uveitis as described earlier. Treatment of EVD complications should be systematic and initiated as soon as possible to prevent severe disabilities such as blindness. Background. Thousands of people have survived Ebola virus disease (EVD) during the ongoing outbreak. However, data about the frequency and risk factors of long-term post-EVD complications remain scarce. We describe the clinical characteristics of EVD survivors followed in a survivor clinic in Freetown, Sierra Leone. Methods. A survivor clinic opened within an Ebola treatment center compound in Freetown, Sierra Leone. At each visit, clinical and psychological assessments were conducted and free treatment was offered. Survivors were referred to a partner's hospitals if their condition could not be managed in the clinic. We used routinely collected data from the clinic to describe long-term complications of EVD and their risk factors. Results. A total of 1001 medical consultations for 166 patients were performed between 3 February and 21 June 2015. The most frequent complaints and diagnoses were arthralgia (n = 129 [77.7%]), fatigue (n = 116 [69.8%]), abdominal pain (n = 90 [54.2%]), headache (n = 87 [52.4%]), anemia (n = 83 [50%]), skin disorders (n = 81 [48.8%]), back pain (n = 54 [32.5%]), and alopecia (n = 53 [31.9%]). Ocular complications were diagnosed in 94 survivors (56.7%); uveitis was the most common (n = 57 [34%]). Survivors were 10 times more likely to develop uveitis post-EVD if they presented with red/injected eyes during the acute phase of their illness. Conclusions. Post-EVD complications among our patients were similar to those described previously and were detected early following the acute phase of disease. Follow-up of survivors should begin immediately after discharge to address sequelae as they arise and reduce the potential for development of long-term disabilities such as blindness.