Preoperative depression is a risk factor for postoperative short-term and long-term cognitive dysfunction in patients with diabetes mellitus

Preoperative depression is a risk factor for postoperative short-term and long-term cognitive dysfunction in patients with diabetes mellitus
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DOI:
10.1007/s00540-010-1072-5
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发表时间:
2011-02-01
影响因子:
2.8
通讯作者:
Mizutani, Akio
Mizutani, Akio
中科院分区:
医学4区
文献类型:
--
作者:
Kadoi, Yuji;Kawauchi, Chikara;Mizutani, Akio

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目的探讨糖尿病患者术前抑郁是否为冠状动脉搭桥术(CABG)术后认知功能障碍的危险因素。方法对90例择期行冠状动脉旁路移植术的糖尿病患者的临床资料进行分析。体外循环期间测量血流动力学数据(动脉和颈静脉血气值)。在手术前,所有患者都接受了21个条目的贝克抑郁问卷,以确定抑郁的存在。并于术前、术后7天、术后6个月进行神经心理测试。结果术后7天认知功能障碍发生率为50%,术后6个月认知功能障碍发生率为23%。年龄、高血压、抑郁症、Sjvo病程(2)
Purpose To identify whether the presence of preoperative depression in patients with diabetes mellitus is a risk factor for postoperative cognitive dysfunction after coronary artery bypass graft (CABG) surgery.Methods Data from 90 patients with diabetes mellitus undergoing elective CABG were analyzed. Hemodynamic data (arterial and jugular venous blood gas values) were measured during cardiopulmonary bypass. Preoperatively, all patients were given the 21-item Beck depression inventory to identify the presence of depression. In addition, all patients underwent a battery of neurological and neuropsychological tests the day before surgery, 7 days after surgery, and 6 months after surgery.Results The rate of cognitive dysfunction was 50% at 7 days and 23% at 6 months after surgery. Age, hypertension, presence of depression, duration of SjvO(2)