Poster Abstracts: 3D geometric morphometric analysis of pygopodid gecko skull morphology and relationship to habitat
Poster Abstracts: 3D geometric morphometric analysis of pygopodid gecko skull morphology and relationship to habitat
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海报摘要：尾足壁虎头骨形态及其与栖息地关系的 3D 几何形态测量分析
DOI：
10.1093/icb/icz004
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发表时间：
2019
影响因子：
2.6
通讯作者：
Bauer, A
中科院分区：
文献类型：
--
作者：
Gurgis, G;Olori, J;Daza, J;Brennan, I;Hutchinson, M;Bauer, A
成功的生殖时机对个体的健康至关重要。虽然大多数脊椎动物依赖于光周期的变化，以诱导季节性青春期，北极地松鼠（AGS）自然经历生殖成熟的褪黑激素和光周期无关的方式。此外，雄性在冬眠期间表现出生殖轴的自发激活，但青春期的时间对外部线索很敏感。我们正在使用电子显微镜检查，定义，并测量超微结构重塑结节部（PT）促甲状腺细胞和垂体前叶（AP）促性腺细胞，AGS过渡到冬眠和生殖季节。我们还测量了内分泌细胞的形态如何与生殖轴输出的测量相对应，包括性腺中类固醇基因表达和血浆性类固醇激素水平的变化。最后，我们正在研究的机制，在冬眠物候可塑性的基础上，并检查AP活动是否可以成为分离的PT信号通路，通过评估细胞重塑放置在一个30 C的房间在冬眠中期，诱导青春期提前发病的男性。我们假设PT形态的变化与青春期的开始和冬眠末期的时间有关，这与光周期无关。AGS生殖控制机制的基本系统水平的调查可能会提供深入了解非光机制，诱导青春期的开始和基础可塑性在青春期的时间。
Successful reproductive timing is essential for the fitness of the individual. While most vertebrates rely on photoperiodic changes to induce seasonal puberty, the arctic ground squirrel (AGS) naturally undergoes reproductive maturation in a melatonin-and photoperiod-independent manner. In addition, males exhibit spontaneous activation of their reproductive axis during hibernation, but the timing of puberty is sensitive to external cues. We are using electron microscopy to examine, define, and measure ultrastructural remodeling in pars tuberalis (PT) thyrotroph cells and anterior pituitary (AP) gonadotroph cells, as the AGS transitions through hibernation and into the reproductive season. We are also measuring how morphology of endocrine cells corresponds with measures of reproductive axis outputs, including changes in steroidogenic gene expression in gonads and plasma sex steroid hormone levels. Finally, we are examing the mechanisms that underly plasticity in hibernation phenology and examining whether AP activity can become dissociated from the PT signaling pathway by assessing cellular remodeling in males placed in a 30 C room during mid-hibernation, which induced early puberty onset. We hypothesize that changes in PT morphology underly puberty initiation and the timing of terminal hibernation in a photoperiod-independent manner. This basic system-level investigation of reproductive control mechanisms in the AGS could potentially provide insight into non-photic mechanisms that induce puberty onset and underlie plasticity in pubertal timing.