Response to Immunization with A and B Human Glycoproteins for the Procurement of Blood Grouping Reagents
Response to Immunization with A and B Human Glycoproteins for the Procurement of Blood Grouping Reagents
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采购血型试剂时使用 A 和 B 人糖蛋白进行免疫接种的反应
DOI：
10.1111/j.1423-0410.1984.tb01590.x
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发表时间：
1984
期刊：
影响因子：
2.7
通讯作者：
P. Hewitt
中科院分区：
文献类型：
--
作者：
M. Contreras;S. Armitage;P. Hewitt
抽象。37例受试者已接受A或B人血型物质免疫。所有受试者的ABO抗体效价均至少增加3倍。使用所得血浆大大提高了我们ABO定型试剂的质量。所有受试者中这些抗体的IgG组分均增加，在大多数免疫后样本中观察到伊加组分。所有O组受试者均出现交叉反应性抗A、B抗体。
Abstract. 37 subjects have been immunized with A or B human blood group substances. All subjects showed at least a threefold increase in potency of their ABO antibodies. Use of the resulting plasma has considerably improved the quality of our ABO grouping reagents. The IgG component of these antibodies increased in all subjects and an IgA component was seen in the majority of post‐immunization samples. All group O subjects developed cross‐reacting anti‐A,B antibodies.