Genetic drift in antagonistic genes leads to divergence in sex-specific fitness between experimental populations of Drosophila melanogaster.
Genetic drift in antagonistic genes leads to divergence in sex-specific fitness between experimental populations of Drosophila melanogaster.
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拮抗基因的遗传漂变导致果蝇实验群体之间性别特异性适应性的差异。
DOI：
10.1111/evo.12032
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Hesketh J
中科院分区：
文献类型：
--
作者：
Hesketh J
男性和女性在他们的生殖角色不同，因此往往是在不同的选择压力下共享的表型性状。理论预测，趋异选择有利于性拮抗等位基因的入侵，这种等位基因增加了一种性别的适应性，而损害了另一种性别。性拮抗作用随后可以通过性别特异性基因表达的进化来解决，从而允许性别在表型上分化。虽然两性异形是很常见的，最近的证据也表明，拮抗性遗传变异继续隔离在许多生物种群。在这里，我们提出的经验数据之间的相互作用性拮抗作用和遗传漂变的人群中，独立发展的标准化条件下。我们证明，小实验种群ofDrosophila melanogaster已经分化的男性和女性的健身，与一些人口显示高的男性，但低的女性健身，而其他人口显示相反的模式。种群间的模式是一致的分化生殖适合性的遗传漂变驱动的性拮抗等位基因。我们讨论的影响，我们的研究结果与维护的拮抗变异细分人群，并考虑更广泛的影响，在健身相关基因的漂移。
Males and females differ in their reproductive roles and as a consequence are often under diverging selection pressures on shared phenotypic traits. Theory predicts that divergent selection can favor the invasion of sexually antagonistic alleles, which increase the fitness of one sex at the detriment of the other. Sexual antagonism can be subsequently resolved through the evolution of sex-specific gene expression, allowing the sexes to diverge phenotypically. Although sexual dimorphism is very common, recent evidence also shows that antagonistic genetic variation continues to segregate in populations of many organisms. Here we present empirical data on the interaction between sexual antagonism and genetic drift in populations that have independently evolved under standardized conditions. We demonstrate that small experimental populations ofDrosophila melanogasterhave diverged in male and female fitness, with some populations showing high male, but low female fitness while other populations show the reverse pattern. The between-population patterns are consistent with the differentiation in reproductive fitness being driven by genetic drift in sexually antagonistic alleles. We discuss the implications of our results with respect to the maintenance of antagonistic variation in subdivided populations and consider the wider implications of drift in fitness-related genes.