PEMPHIGUS NEONATORUM, OR BULLOUS IMPETIGO CONTAGIOSA OF THE NEW-BORN
PEMPHIGUS NEONATORUM, OR BULLOUS IMPETIGO CONTAGIOSA OF THE NEW-BORN
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新生儿天疱疮或新生儿大疱性传染性脓疱病
DOI：
10.1001/jama.1909.92550050007002e
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发表时间：
1909
期刊：
影响因子：
--
通讯作者：
O. Foerster
中科院分区：
文献类型：
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作者：
O. Foerster
1773年，Oehme首次将天疱疮描述为一种独立的疾病。在此之前，它一直与梅毒混淆，直到上个世纪中期，仍有许多人认为它是梅毒的起源。关于这个问题的作家突出了感情的大疱特征，它经常发生在产科病房，弃婴收容所，以及助产士的实践中，以及它的可变过程，在某些情况下是良性的，在其他情况下呈现出惊人的死亡率。后一种观察早期导致其分为良性和恶性形式。也注意到这种疾病从婴儿转移到其他儿童或成人的可能性，许多作者观察到，传播到年龄较大的儿童或成人会导致临床特征的决定性变化。
Pemphigus neonatorum was first described as an independent disease by Oehme in 1773. Previous to that time it had been confounded with syphilis, and until almost the middle of the last century there were many who still considered it as syphilitic in origin. Writers on the subject gave prominence to the bullous character of the affection, to its frequent occurrence in epidemics—especially in obstetric wards, foundling asylums, and in the practice of midwives—and to its variable course, benign in some instances, and in others presenting an alarming mortality. The latter observation early led to its division into a benign and malignant form. The possibility of a transference of the disease from infants to other children or to adults was also noted, and many writers observed that transmission to older children or adults resulted in a decided change in the clinical character of the