Kazakhstani native cattle reveal highly divergent mtDNA from Bos taurus and Bos indicus lineages with an absence of Bos indicus Y chromosome
Kazakhstani native cattle reveal highly divergent mtDNA from Bos taurus and Bos indicus lineages with an absence of Bos indicus Y chromosome
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DOI：
10.1111/asj.13128
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发表时间：
2019-01-01
影响因子：
2
通讯作者：
Mannen, Hideyuki
中科院分区：
文献类型：
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作者：
Yamanaka, Hayate;Murata, Kako;Mannen, Hideyuki
哈萨克斯坦是最大的内陆国家，拥有从新月沃土到亚洲的两条重要牲畜繁殖路线。因此，有关哈萨克斯坦牛的遗传信息对于了解中亚牛的繁殖历史和遗传混合物非常重要。本研究对122头哈萨克斯坦本地黄牛线粒体DNA D-loop区全序列和SRY基因多态性进行了分析。D-loop序列揭示了79种线粒体单倍型，主要单倍型群为T和I。普通牛亚单倍群由T（3.3%）、T1（2.5%）、T2（2.5%）和T4（0.8%）组成，此外还有占优势的T3亚单倍群（86.9%）和印度牛亚单倍群I1（4.1%）。随后，我们调查了普通牛和印度牛的父系谱系，然而，所有哈萨克斯坦牛都显示具有普通牛起源的Y染色体。虽然高度分歧的线粒体DNA亚单倍群在哈萨克斯坦牛可能是由于地理上接近哈萨克斯坦的驯化中心的肥沃的新月，没有牛的印度Y染色体可以解释由解耦的渗入动态的母系和父系血统。这些遗传信息将有助于了解中亚牛的遗传多样性和繁殖历史。
Kazakhstan is the largest landlocked country and contains two important propagation routes for livestock from the Fertile Crescent to Asia. Therefore, genetic information about Kazakhstani cattle can be important for understanding the propagation history and the genetic admixture in Central Asian cattle. In the present study, we analyzed the complete mtDNA D-loop sequence and SRY gene polymorphism in 122 Kazakhstani native cattle. The D-loop sequences revealed 79 mitochondrial haplotypes, with the major haplogroups T and I. The Bos taurus subhaplogroups consisted of T (3.3%), T1 (2.5%), T2 (2.5%), and T4 (0.8%) in addition to the predominant subhaplogroup T3 (86.9%), and the Bos indicus subhaplogroup of I1 (4.1%). Subsequently, we investigated the paternal lineages of Bos taurus and Bos indicus, however, all Kazakhstani cattle were shown to have Y chromosome of Bos taurus origin. While highly divergent mtDNA subhaplogroups in Kazakhstani cattle could be due to the geographical proximity of Kazakhstan with the domestication center of the Fertile Crescent, the absence of Bos indicus Y chromosomes could be explained by a decoupling of the introgression dynamics of maternal and paternal lineages. This genetic information would contribute to understanding the genetic diversity and propagation history of cattle in Central Asia.