Complementary & alternative management of Parkinson's disease: an evidence-based review of eastern influenced practices.
Complementary & alternative management of Parkinson's disease: an evidence-based review of eastern influenced practices.
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DOI：
10.14802/jmd.14009
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发表时间：
2014-10
影响因子：
3.9
通讯作者：
Zadikoff C
中科院分区：
文献类型：
--
作者：
Bega D;Zadikoff C
与西方世界相比，亚洲帕金森氏症(PD)的患病率似乎较低。目前尚不清楚这是否与东方医疗保健中普遍使用传统医学有关，但在韩国等国家，补充和替代医学(CAM)模式的使用率可能高达76%。在帕金森病患者中，草药、保健食品和针灸是世界各地越来越多的干预措施。韩国、中国、印度和日本等国家长期以来一直接受传统医学，并将其纳入PD等疾病的现代管理，但对各种CAM模式的研究仍处于初级阶段，限制了许多治疗方法的循证建议。我们回顾了关于CAM治疗帕金森病的文献，重点是心身干预和天然产物。基于仅限于随机对照试验的证据，我们发现，心身干预通常是有效的体力活动形式，可能会促进良好的坚持，并可能减少与帕金森病相关的残疾。根据目前的数据，像太极和舞蹈这样的方式对帕金森病是安全和有益的，但还需要更好的研究来评估其他常用方式的效果，如瑜伽和针灸。此外，尽管东方国家使用草药和植物已有数百年的经验，尽管有大量临床前数据表明营养抗氧化剂作为帕金森病神经保护剂的有益作用，但没有足够的临床证据表明，任何维生素、食品添加剂或补充剂可以改善运动功能或延缓帕金森病的疾病进展。
The prevalence of Parkinson’s disease (PD) appears to be lower in Asia compared to the Western world. It is unclear if this is related to the ubiquitous use of traditional medicine in Eastern healthcare, but the use of complementary and alternative medicine (CAM) modalities in countries like Korea may be as high as 76%. Among patients with PD, herbal medicines, health supplement foods, and acupuncture are interventions which are increasingly used throughout the world. Countries like Korea, China, India, and Japan have long embraced and incorporated traditional medicine into modern management of conditions such as PD, but research into various CAM modalities remains in its infancy limiting evidence-based recommendations for many treatments. We reviewed the literature on CAM treatments for PD, focusing on mind-body interventions and natural products. Based on evidence limited to randomized-controlled trials we found that mind-body interventions are generally effective forms of physical activity that are likely to foster good adherence and may reduce disability associated with PD. Based on the current data, modalities like Tai Chi and dance are safe and beneficial in PD, but better studies are needed to assess the effects of other frequently used modalities such as yoga and acupuncture. Furthermore, despite centuries of experience using medicinal herbs and plants in Eastern countries, and despite substantial preclinical data on the beneficial effects of nutritional antioxidants as neuroprotective agents in PD, there is insufficient clinical evidence that any vitamin, food additive, or supplement, can improve motor function or delay disease progression in PD.