Digital image capture for high-resolution medical x-ray diagnostics
Digital image capture for high-resolution medical x-ray diagnostics
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用于高分辨率医学 X 射线诊断的数字图像捕获
DOI：
10.1117/12.2321166
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
Akif, Adil
中科院分区：
文献类型：
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作者：
Mostovych, Nicholas A.;Morse, Theodore F.;Gupta, Rajiv;Murphy, Timothy P.;Weber, Peter M.;Cherepy, Nerine J.;Adams, Bernhard W.;Bifano, Thomas G.;Stankus, Brian;Akif, Adil
我们已经证明了一个高分辨率（10微米）的X射线闪烁体板作为间接X射线探测系统的一部分。 闪烁器板通常与基于非晶硅的光电二极管的二维阵列集成。 本文介绍了一种替代的数字采集系统，利用低成本的CCD/CMOS相机。 我们的探测器具有广泛的潜在应用，但最初的目标应用是乳房X线摄影。 全视野乳房X线摄影要求成像面积为180 mm x 240 mm或更大。 非常大的CCD/CMOS传感器最近已经被开发用于高分辨率相机，例如具有202 mm x 205 mm传感器尺寸的250像素佳能相机，并且可以想象地与我们的高分辨率闪烁体板匹配，而无需任何用于放大的介入光学器件。 然而，由于低产量和高成本考虑，这种大格式CCD/CMOS传感器的可用性有限。 另一方面，小尺寸（36 mm x 24 mm）和中等尺寸（44 mm x 33 mm）的基于CCD/CMOS的光电二极管由于其在移动的设备和消费者相机的大市场中的应用而以低成本变得广泛可用。 因此，我们开发了一种简单的光学方案，利用四个小型或中型CCD/CMOS相机捕捉更大的，高分辨率的图像。 目前用于筛查乳房X线摄影术的系统分辨75-100微米的组织特征。 在初步乳房X线摄影筛查期间发现的可疑特征在诊断性乳房X线摄影测试期间进一步调查，该测试使用聚焦在可疑病变上的高分辨率探测器。通常，询问小于100 mm x 80 mm的区域，这是我们的高分辨率闪烁板的当前最大尺寸。 我们表明，诊断乳腺X射线摄影，超过100毫米× 80毫米的面积，可以使用我们的系统进行功能分辨率低至7微米。
We have demonstrated a high resolution (10 micron) X-ray scintillator plate as part of an indirect X-ray detection system. Scintillator plates are typically integrated with a 2-dimensional array of photodiodes based upon amorphous Si. This paper describes an alternative digital capture system that leverages low cost CCD/CMOS cameras. Our detector has a broad set of potential applications, however the initial target application is mammography. Full-field mammography mandates an imaging area of 180mm x 240mm or larger. Very large CCD/CMOS sensors have recently been developed for high resolution cameras, such as the 250-pixel Canon camera which has sensor dimensions of 202mm x 205mm, and could conceivably be matched to our high-resolution scintillator plate without any intervening optics for magnification. However, such large format CCD/CMOS sensors have limited availability because of low production yields and high cost considerations. On the other hand, small form (36mm x 24mm) and medium format (44mm x 33mm) CCD/CMOS-based photodiodes have become widely available at low cost due to their applications in the large markets of mobile devices and consumer cameras. We have therefore developed a simple optical scheme for utilizing four small or medium format CCD/CMOS cameras to capture a larger, high-resolution image. Current systems employed in screening mammography resolve tissue features of 75-100 microns. Suspicious features found during preliminary mammographic screenings are further investigated during diagnostic mammographic tests which use a high-resolution detector that is focused over the suspicious lesion. Typically, an area less than 100mm x 80mm, the current maximum size of our high-resolution scintillation plate, is interrogated. We show that diagnostic mammography, over an area of 100mm x 80mm, could be performed using our system with a feature resolution down to 7 microns.
影响因子：
35
作者：
Yakunin S;Sytnyk M;Kriegner D;Shrestha S;Richter M;Matt GJ;Azimi H;Brabec CJ;Stangl J;Kovalenko MV;Heiss W
通讯作者：
Heiss W
用于伽马能谱和中子主动询问的载铋塑料闪烁体
DOI：
--
发表时间：
2012
期刊：
Nuclear Science Symposium and Medical Imaging Conference
影响因子：
--
作者：
N. Cherepy;R. Sanner;T. Tillotson;S. Payne;P. Beck;S. Hunter;L. Ahle;P. Thelin
通讯作者：
P. Thelin
用于伽马射线光谱的载铋塑料闪烁体
DOI：
--
发表时间：
2012
期刊：
影响因子：
--
作者：
B. L. Rupert;N. Cherepy;B. Sturm;R. Sanner;S. Payne
通讯作者：
S. Payne