Duration of the distal compound muscle action potential for diagnosis of chronic
Duration of the distal compound muscle action potential for diagnosis of chronic
复制标题
远端复合肌肉动作电位的持续时间用于诊断慢性
DOI：
10.1097/wnp.0000000000000045
复制
发表时间：
2014
影响因子：
2.4
通讯作者：
Sekiguchi
中科院分区：
文献类型：
--
作者：
Isose S;Misawa S;Sonoo M;Shimuzu T;Oishi C;Shibuya K;Nasu S;Sekiguchi
目的：在目前慢性炎性脱髓鞘性多发性神经病的电诊断标准中，远端复合肌肉动作电位（DCMAP）持续时间的截止值是使用20 Hz的肌电图低切滤波器设置定义的。我们的目的是评估低切滤波器对DCMAP持续时间（10与20 Hz）的影响。方法：我们前瞻性地测量了130名正常对照和42例患者的DCMAP持续时间，符合欧洲神经学会联合会/周围神经学会对典型慢性炎性脱髓鞘性多发性神经病的诊断标准。当临界值定义为正常上限（ULN，平均值+2.5 SD）时，10 Hz记录的灵敏度/特异性为67%/95%，20 Hz记录的灵敏度/特异性为69%/95%。这种诊断的准确性是相似的，由接收器操作特性analysis.Conclusions：远端复合肌肉动作电位持续时间显着影响的低切肌电图滤波器设置，但至少10和20 Hz，诊断准确性是相似的。
Purpose:In current electrodiagnostic criteria for chronic inflammatory demyelinating polyneuropathy, the cutoff values of distal compound muscle action potential (DCMAP) duration are defined using electromyogram low-cut filter setting of 20 Hz. We aimed to assess effects of low-cut filter on DCMAP duration (10 vs. 20 Hz).Methods:We prospectively measured DCMAP duration in 130 normal controls and 42 patients, fulfilling diagnostic criteria for typical chronic inflammatory demyelinating polyneuropathy by European Federation of Neurological Societies/Peripheral Nerve Society.Results:Distal compound muscle action potential duration was significantly shortened with 20-Hz than 10-Hz filtering. When the cutoff values were defined as the upper limit of normal (ULN, mean+ 2.5 SD), the sensitivity/specificity was 67%/95% in 10-Hz recordings, and 69%/95% in 20-Hz recordings. This diagnostic accuracy was similar to that defined by receiver operating characteristic analyses.Conclusions:Distal compound muscle action potential duration significantly affected by the low-cut electromyogram filter setting, but with at least 10 and 20 Hz, the diagnostic accuracy is similar.