A COMMUNITY-BASED STUDY OF THE EPIDEMIOLOGY OF ASTHMA - INCIDENCE RATES, 1964-1983
A COMMUNITY-BASED STUDY OF THE EPIDEMIOLOGY OF ASTHMA - INCIDENCE RATES, 1964-1983
复制标题
DOI：
10.1164/ajrccm/146.4.888
复制
发表时间：
1992-10-01
期刊：
影响因子：
--
通讯作者：
SILVERSTEIN, MD
中科院分区：
文献类型：
--
作者：
YUNGINGER, JW;REED, CE;SILVERSTEIN, MD
为了确定明尼苏达州罗切斯特从1964年1月1日至1983年12月31日哮喘发病率是否增加，我们使用了一种基于人口的计算机连接医疗诊断系统，以识别诊断为哮喘或其他类似哮喘的疾病的个人医疗记录。所有记录均采用明确的预先确定的诊断标准进行审查;我们确定了3，622例哮喘事件病例，包括明确的哮喘（n = 1，547），可能的哮喘（n = 952）和单一喘息发作（n = 1，123）。经年龄和性别校正的明确+很可能哮喘的年发病率从1964年的183/10万上升到1983年的284/10万。这一上升完全是由于儿童和青少年（年龄范围，1至14岁）发病率增加所致; 1岁以下婴儿和成人的发病率保持不变。对于明确+很可能的哮喘病例，从婴儿期到9岁和50岁以上的人群，男性的发病率高于女性;从15岁到49岁，女性的发病率高于男性。男性发病时的中位年龄为3岁，女性为8岁。我们的结论是，哮喘开始于幼儿期，男性发病率较高，发病较早，从1964年至1983年发病率的增加只发生在儿童和青少年。
To determine whether the incidence of asthma had increased in Rochester, Minnesota, from January 1, 1964 through December 31, 1983, we used a population-based computer-linked medical diagnosis system to identify individual medical records with diagnoses of asthma or other conditions mimicking asthma. All records were reviewed using explicit predetermined diagnostic criteria; we identified 3,622 incident cases of asthma, including definite asthma (n = 1,547), probable asthma (n = 952), and single wheezing episodes (n = 1,123). The annual age- and sex-adjusted incidence of definite + probable asthma rose from 183 per 100,000 In 1964 to 284 per 100,000 In 1983. This rise was entirely accounted for by increased incidence rates in children and adolescents (age range, 1 to 14 yr); incidence rates for infants younger than 1 yr of age and for adult remained constant. For definite + probable asthma cases, the incidence rates for males were higher than for females from infancy through 9 yr of age and for persons older then 50; Incidence rates for females were higher then for males from 15 through 49 yr of age. The median age at onset was 3 yr for males and 8 yr for females. We conclude that asthma begins in early childhood, with a higher incidence and earlier onset in males, and that the increase in incidence rates seen from 1964 to 1983 occurred only in children and in adolescents.