Microcystic adnexal carcinoma arising within a nevus sebaceus.
Microcystic adnexal carcinoma arising within a nevus sebaceus.
复制标题
皮脂腺痣内产生的微囊性附件癌。
作者：
Nektarios I. Lountzis;J. Junkins;M. Uberti;R. Elenitsas
皮脂痣（NS）是一种发生在面部和头皮上的先天性皮肤病变，与各种癌症的发展有关。我们报告一位62岁的男性，在头皮上发生微囊状附属器癌（MAC），并进行皮肤切片及苏木精伊红染色检查。连续切片显示NS典型的乳头状瘤病，局灶性变化与乳头状囊腺瘤一致。邻近乳头状囊腺瘤的区域含有局部延伸到皮下层的小上皮岛。囊状岛嵌在结缔组织间质中，界限不清，与MAC一致。此病例在NS中罕见发现MAC。
Nevus sebaceus (NS) is a congenital skin lesion arising on the face and scalp that has been linked to the development of various carcinomas. We describe a case of microcystic adnexal carcinoma (MAC) arising in an NS on the scalp of a 62-year-old man. Excisional skin biopsy and hematoxylin and eosin stains were performed to examine the specimen. Serial sections revealed papillomatosis typical of NS, with focal changes consistent with syringocystadenoma papilliferum. Adjacent to the syringocystadenoma papilliferum was an area containing small epithelial islands that extended focally into the subcutaneous layer. The cystic islands were embedded in a desmoplastic stroma with poor circumscription, consistent with MAC. This case presents a rare finding of MAC within an NS.