MATERNAL-EFFECT SELFISH GENES IN FLOUR BEETLES
MATERNAL-EFFECT SELFISH GENES IN FLOUR BEETLES
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DOI：
10.1126/science.1566060
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发表时间：
1992-04-03
期刊：
影响因子：
56.9
通讯作者：
DENELL, RE
中科院分区：
文献类型：
--
作者：
BEEMAN, RW;FRIESEN, KS;DENELL, RE
一个以前未知的类占主导地位的，母亲效应致死M因子被发现是广泛存在于自然种群的面粉甲虫，赤拟谷盗，收集在几个大陆。这些因子整合到宿主染色体的可变位置，并显示出显着的自我选择的属性，通过母体效应致死所有孵化不继承该因子本身的副本。后代被父系或母系遗传的拷贝所拯救。因此，携带M的染色体以其非M同系物为代价而得以延续。映射到基因组不同区域的M因子并不能拯救彼此的母体效应致死性。表达这些特性的因子被预测在群体中传播，即使在没有任何额外的选择优势的情况下。相似的因素也发生在相关物种T。混乱。
A previously unknown class of dominant, maternal-effect lethal M factors was found to be widespread in natural populations of the flour beetle, Tribolium castaneum, collected on several continents. Such factors are integrated into the host chromosomes at variable locations and show the remarkable property of self-selection by maternal-effect lethality to all hatchlings that do not inherit a copy of the factor itself. Offspring are rescued by either paternally or maternally inherited copies. The M-bearing chromosome is thereby perpetuated at the expense of its non-M homolog. M factors that map to different regions of the genome do not rescue one another's maternal-effect lethality. Factors expressing these properties are predicted to spread in a population, even in the absence of any additional selective advantage. Similar factors also occur in the related species T. confusum.