Separation and Purification of Flavonoid from Ginkgo Extract by Polyamide Resin
Separation and Purification of Flavonoid from Ginkgo Extract by Polyamide Resin
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DOI：
10.1080/01496395.2010.487844
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发表时间：
2010-01-01
影响因子：
2.8
通讯作者：
Xia, Shuqin
中科院分区：
文献类型：
--
作者：
Zhang, Jing;Hayat, Khizar;Xia, Shuqin
研究了一种从银杏提取物中提取黄酮类化合物的高效分离工艺。聚酰胺树脂具有良好的吸附性能，25 ℃时的吸附速率符合Langmuir等温式。采用动态吸附-解吸实验优化银杏叶提取物中总黄酮的分离工艺。经一次提取后，总黄酮含量由24.0%提高到55.0%。该方法为黄酮类化合物的大规模分离纯化提供了一条可行的途径。
An efficient separation process of flavonoid from Ginkgo extract was developed in this study. Polyamide resin offered the fine adsorption capacity, and its adsorption rate at 25 degrees C fitted well to the Langmuir isotherm. Dynamic adsorption and desorption experiments were conducted to optimize the separation process of total flavonoids from the Ginkgo extract. After one run, the content of total flavonoids increased from 24.0% to 55.0%. The method will provide a potential approach for large-scale separation and purification of flavonoid for its wide pharmaceutical use.