Molecular Imaging Biomarkers for Oncology Clinical Trials
Molecular Imaging Biomarkers for Oncology Clinical Trials
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DOI：
10.2967/jnumed.113.126128
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发表时间：
2014-04-01
影响因子：
9.3
通讯作者：
Clark, Amy S.
中科院分区：
文献类型：
--
作者：
Mankoff, David A.;Pryma, Daniel A.;Clark, Amy S.
生物标志物可用于表征疾病状态或预测疾病行为。癌症生物标志物通常依赖于血液或组织的测定;然而，分子成像作为癌症生物标志物具有有前途的补充作用。这篇“聚焦分子成像”文章回顾了生物标志物在指导癌症临床试验和临床实践中的作用，沿着分子成像在当前和未来癌症生物标志物中的应用。
Biomarkers can be used to characterize disease status or predict disease behavior. Cancer biomarkers have typically relied on assays of blood or tissue; however, molecular imaging has a promising and complementary role as a cancer biomarker. This "Focus on Molecular Imaging" article reviews the current role of biomarkers to direct cancer clinical trials and clinical practice, along with current and future cancer biomarker applications of molecular imaging.