Motivation, recruitment, and screening of volunteers for a phase I/II HIV preventive vaccine trial in Thailand
Motivation, recruitment, and screening of volunteers for a phase I/II HIV preventive vaccine trial in Thailand
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DOI：
10.1097/00042560-199806010-00009
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发表时间：
1998-06-01
期刊：
影响因子：
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通讯作者：
Khamboonruang, C
中科院分区：
文献类型：
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作者：
Jenkins, RA;Chinaworapong, S;Khamboonruang, C
从招募和筛选阶段I/II预防HIV-1疫苗试验在泰国的数据进行了评价，在每个阶段的参与相关性。相关因素包括人口统计学变量、对试验感兴趣的动机以及与沟通和联系相关的因素。通过不同的方法在两个地点招募参与者。大多数预筛选者报告了对试验感兴趣的利他动机，献血者成为一个可能特别利他的群体。研究结果表明，招募和筛选期间的损耗存在研究中心差异，但在疫苗试验的入组方面没有差异。献血和愿意在家里通过电话联系与进行和保持筛查预约显着相关。
Data from recruitment and screening for a phase I/II preventive HIV-1 vaccine trial in Thailand were evaluated with respect to correlates of participation at each phase. Correlates included demographic variables, motivation for interest in the trial, and factors related to communication and contact. Participants were recruited at two sites through varied methods. The majority of prescreenees reported altruistic motives for interest in the trial and blood donors emerged as a group that may have been particularly altruistic. Findings indicated site differences in attrition during recruitment and screening, but not in enrollment into the vaccine trial. Blood donation and willingness to be contacted by phone at home were significantly related to making and keeping screening appointments.