Sensitivity enhancement in capillary electrophoresis and their applications for analyses of pharmaceutical and related biochemical substances
Sensitivity enhancement in capillary electrophoresis and their applications for analyses of pharmaceutical and related biochemical substances
复制标题
DOI：
10.1002/elps.202100236
复制
发表时间：
2021-12
期刊：
影响因子：
2.9
通讯作者：
L. Suntornsuk;O. Anurukvorakun
中科院分区：
文献类型：
--
作者：
L. Suntornsuk;O. Anurukvorakun
本综述旨在阐述毛细管电泳 (CE) 中的灵敏度增强方法及其在药物和相关生化物质分析中的应用。文章的前两部分介绍了CE的简介和原理。主要部分侧重于 CE 灵敏度提高策略，包括检测器和毛细管技术以及预浓缩技术。 2018-2021 年期间对这些技术在药物和生物医学物质分析中的应用进行了调查。
This review aims to illustrate sensitivity enhancement methods in capillary electrophoresis (CE) and their applications for pharmaceutical and related biochemical substance analyses. The first two parts of the article describe the introduction and principle of CE. The main part focuses on strategies for sensitivity improvement in CE including detector and capillary technologies and preconcentration techniques. Applications of these techniques for pharmaceutical and biomedical substance analyses are surveyed during the years 2018–2021.