Automated MALDI matrix deposition method with inkjet printing for imaging mass spectrometry
Automated MALDI matrix deposition method with inkjet printing for imaging mass spectrometry
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DOI：
10.1021/ac070958d
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发表时间：
2007-09-01
影响因子：
7.4
通讯作者：
Yost, Richard A.
中科院分区：
文献类型：
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作者：
Baluya, Dodge L.;Garrett, Timothy J.;Yost, Richard A.
基质辅助激光解吸/电离（MALDI）的组织样品上仔细的基质沉积对于产生可再现的分析物离子信号至关重要。传统的基质沉积方法通常被认为是一门艺术而不是一门科学，具有显著的样品间差异。在这里，我们报告了一种自动化的方法，矩阵沉积，采用台式喷墨打印机（
Careful matrix deposition on tissue samples for matrixassisted laser desorption/ionization (MALDI) is critical for producing reproducible analyte ion signals. Traditional methods for matrix deposition are often considered an art rather than a science, with significant sample-to-sample variability. Here we report an automated method for matrix deposition, employing a desktop inkjet printer (