Danazol therapy for cyclic thrombocytopenia.
Danazol therapy for cyclic thrombocytopenia.
复制标题
达那唑治疗周期性血小板减少症。
DOI：
10.1002/ajh.2830360213
复制
发表时间：
1991
影响因子：
12.8
通讯作者：
Harrington,WJ
中科院分区：
文献类型：
--
作者：
Rocha,R;Horstman,L;Ahn,YS;Mylvaganam,R;Harrington,WJ
Cyclic thrombocytopenia is a rare disease characterized by cyclic oscillations of platelet counts from very low to normal or higher. Severe hemorrhage may occur during the thrombocytopenic phase. To date, treatments for this disorder have been disappointing. Its pathophysiology is unknown. We report a successful outcome using danazol therapy.It can be argued that the long‐term outcome was due to spontaneous remission. However, significant improvement was noted from the outset of danazol therapy, and further improvement with long‐term therapy, as seen in the response of chronic ITP to danazol therapy. Danazol may offer lasting benefit in cyclic thrombocytopenia.
