PRESENTATION, DURATION OF SYMPTOMS AND STAGING OF COLORECTAL-CARCINOMA
PRESENTATION, DURATION OF SYMPTOMS AND STAGING OF COLORECTAL-CARCINOMA
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DOI：
10.1111/j.1445-2197.1991.tb00190.x
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发表时间：
1991-02-01
期刊：
影响因子：
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通讯作者：
YEONG, ML
中科院分区：
文献类型：
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作者：
KYLE, SM;ISBISTER, WH;YEONG, ML
回顾了 1987 年 4 月至 1989 年 5 月间在惠灵顿和 Kenepuru 医院根据澳大利亚临床病理系统 (ACPS) 进行的前瞻性记录、连续系列 155 例临床和病理分期的结直肠癌标本。 155 名患者中，有 146 名患者的临床记录可供回顾性审查。 排便习惯改变、直肠出血和腹痛是最常见的症状。 35 名患者因急诊就诊，其中 26 名患者出现梗阻，9 名患者出现穿孔。 腹痛导致最早进行手术干预。 诊断前症状的中位持续时间为 3 个月。 肿瘤分期和症状持续时间之间不存在相关性。 在结直肠癌症状阶段进行早期诊断不太可能显着改善总体生存率。
A prospectively recorded, consecutive series of 155 colorectal carcinoma specimens clinically and pathologically staged according to the Australian Clinico-pathological System (ACPS) between April 1987 and May 1989 at Wellington and Kenepuru Hospitals is reviewed. Clinical records were available for retrospective review for 146 of the 155 patients. Change in bowel habit, rectal bleeding and abdominal pain were the most common presenting symptoms. Thirty-five patients presented as emergencies, twenty-six with obstruction and nine with perforation. Abdominal pain resulted in the earliest surgical intervention. The median duration of symptoms prior to diagnosis was 3 months. No correlation existed between tumour stage and duration of symptoms. Earlier diagnosis during the symptomatic phase of colorectal carcinoma is unlikely to contribute significantly to improved overall survival.