Bacterial associations reveal spatial population dynamics in Anopheles gambiae mosquitoes.
Bacterial associations reveal spatial population dynamics in Anopheles gambiae mosquitoes.
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DOI：
10.1038/srep22806
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发表时间：
2016-03-10
影响因子：
4.6
通讯作者：
Terenius O
中科院分区：
文献类型：
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作者：
Buck M;Nilsson LK;Brunius C;Dabiré RK;Hopkins R;Terenius O
疟疾这一无法忍受的负担长期困扰着人类，在21世纪，消除疟疾的前景是一个乐观的、但可以实现的目标。然而，需要对蚊子种群的空间结构有广泛的了解，以便制定有效的预防疟疾传播的干预措施。我们假设与蚊子相关的微生物群反映了不同环境中细菌的获取。通过对安氏菌的全身菌群分析。通过16s扩增子测序，我们发现不同的环境给了每只蚊子一个特定的细菌谱。此外，细菌谱提供了蚊子种群整体空间动态的精确预测信息，并表明蚊子在一个元种群网络中形成了明确的局部种群。我们认为，使用微生物群作为种群结构的代理将极大地有助于提高世界各地媒介干预的性能。
The intolerable burden of malaria has for too long plagued humanity and the prospect of eradicating malaria is an optimistic, but reachable, target in the 21st century. However, extensive knowledge is needed about the spatial structure of mosquito populations in order to develop effective interventions against malaria transmission. We hypothesized that the microbiota associated with a mosquito reflects acquisition of bacteria in different environments. By analyzing the whole-body bacterial flora of An. gambiae mosquitoes from Burkina Faso by 16 S amplicon sequencing, we found that the different environments gave each mosquito a specific bacterial profile. In addition, the bacterial profiles provided precise and predicting information on the spatial dynamics of the mosquito population as a whole and showed that the mosquitoes formed clear local populations within a meta-population network. We believe that using microbiotas as proxies for population structures will greatly aid improving the performance of vector interventions around the world.