Importins and exportins: how to get in and out of the nucleus.
Importins and exportins: how to get in and out of the nucleus.
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DOI：
10.1016/s0968-0004(98)01204-3
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发表时间：
1998-05
影响因子：
13.8
通讯作者：
K. Weis
中科院分区：
文献类型：
--
作者：
K. Weis
每分钟，数百万蛋白质和RNA分子必须在真核细胞的细胞质和细胞核之间运输。不同的核输入和输出途径的介质，受体和辅助因子的表征提供了一个一瞥的分子机制，负责这些贩运事件。看来，入站和出站交通是介导的相关运输因子，可分为importins和exportins的蛋白质家族。
Every minute, several million protein and RNA molecules must be transported between the cytoplasm and the nucleus of a eukaryotic cell. The characterization of mediators, receptors and accessory factors for different nuclear import and export pathways has provided a glimpse at the molecular machinery that is responsible for these trafficking events. It appears that both inbound and outbound traffic is mediated by a protein family of related transport factors that can be classified as importins and exportins.