Initial feasibility and acceptability of a comprehensive intervention for methamphetamine-using pregnant women in South Africa.
Initial feasibility and acceptability of a comprehensive intervention for methamphetamine-using pregnant women in South Africa.
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DOI：
10.1155/2014/929767
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发表时间：
2014-01-01
影响因子：
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通讯作者：
Wechsberg, Wendee M
中科院分区：
文献类型：
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作者：
Jones, Hendree E;Myers, Bronwyn;Wechsberg, Wendee M
本研究的目的是确定可行性，可接受性，并在南非开普敦孕妇中的甲基苯丙胺使用和艾滋病毒性风险的妇女为重点的干预措施的初步疗效。进行了一项两组随机试点研究，比较了以女性为中心的甲基苯丙胺使用和相关性风险行为的干预与心理教育条件。参与者是经常使用甲基苯丙胺的孕妇，在前一个月有无保护措施的性行为，并且是HIV阴性。主要的产妇结局是过去30天内甲基苯丙胺的使用，过去30天内无保护性行为的频率，以及产前产科预约的数量。主要新生儿结局为住院时间、出生体重和分娩时胎龄。在最初可能符合条件的57名妇女中，只有4人拒绝参加。在36名合格并登记的妇女中，92%完成了所有四次干预。这两种情况下的妇女都大大减少了甲基苯丙胺的使用和无保护性行为的数量。因此，提供综合干预措施，以解决甲基苯丙胺的使用和使用甲基苯丙胺的孕妇中的艾滋病毒风险行为在南非是可行的。需要进一步测试这些干预措施，以解决这一弱势群体中使用甲基苯丙胺的问题。
The purpose of the present study was to determine the feasibility, acceptability, and initial efficacy of a women-focused intervention addressing methamphetamine use and HIV sexual risk among pregnant women in Cape Town, South Africa. A two-group randomized pilot study was conducted, comparing a women-focused intervention for methamphetamine use and related sexual risk behaviors to a psychoeducational condition. Participants were pregnant women who used methamphetamine regularly, had unprotected sex in the prior month, and were HIV-negative. Primary maternal outcomes were methamphetamine use in the past 30 days, frequency of unprotected sexual acts in the past 30 days, and number of antenatal obstetrical appointments attended. Primary neonatal outcomes were length of hospital stay, birth weight, and gestational age at delivery. Of the 57 women initially potentially eligible, only 4 declined to participate. Of the 36 women who were eligible and enrolled, 92% completed all four intervention sessions. Women in both conditions significantly reduced their methamphetamine use and number of unprotected sex acts. Therefore, delivering comprehensive interventions to address methamphetamine use and HIV risk behaviors among methamphetamine-using pregnant women is feasible in South Africa. Further testing of these interventions is needed to address methamphetamine use in this vulnerable population.