Safety, Acceptance, and Physiologic Effects of Sauna Bathing in People With Chronic Heart Failure: A Pilot Report
Safety, Acceptance, and Physiologic Effects of Sauna Bathing in People With Chronic Heart Failure: A Pilot Report
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DOI：
10.1016/j.apmr.2008.06.029
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发表时间：
2009-01-01
影响因子：
4.3
通讯作者：
Tei, Chuwa
中科院分区：
文献类型：
--
作者：
Basford, Jeffrey R.;Oh, Jae K.;Tei, Chuwa
目的：进行一项试点研究，并对慢性心力衰竭（CHF）患者在中等温度下接受监督桑拿浴的安全性和可接受性进行初步评估。次要措施包括其对运动耐量和神经内分泌concentration.Design的影响：随机，对照，交叉trial.Setting：物理医学和康复clinic.Participants：6名男性和3名女性（年龄，62- 87岁）与纽约心脏协会III级和IV级CHF.Interventions：受试者被随机分为2组，并告诉他们保持正常的药物和活动方案。然后，一组开始每周3次，为期4周的桑拿浴计划，温度为60 +/- 1摄氏度，而另一组则继续他们的日常活动和药物治疗。然后，他们被逆转了。会议的长度为15分钟，但延长了额外的5分钟，口腔温度增加小于1.0摄氏度。主要结果测量：患者接受，明尼苏达州生活与心力衰竭问卷（MLWHFQ）评分;跑步机运动时间和血浆肾上腺素，去甲肾上腺素，醛固酮，心房自然因子，肾上腺髓质素和内皮素。桑拿浴的耐受性良好，没有不良反应的报告。MLWHFQ评分和跑步机耐力的改善在组间基础上没有达到统计学显著性，但在桑拿后比对照期更显著。神经内分泌浓度显示没有明确的桑拿治疗组间的统计学显着差异（P= 0.049），发现只有在去甲肾上腺素的24% reduction.Conclusions的情况下，桑拿浴温和和监督的条件下，这项研究似乎是耐受性良好，可能是安全的人与CHF。需要更多的研究来进一步评估这种方法的安全性和潜在益处。
Objectives: To perform a pilot Study and make a preliminary assessment of the safety and acceptance of supervised sauna bathing at moderate temperatures in people with chronic heart failure (CHF). Secondary measures included its impact on exercise tolerance and neuroendocrine concentrations.Design: Randomized, controlled, cross-over trial.Setting: Physical medicine and rehabilitation clinic.Participants: Six men and 3 women (age, 62-87y) with New York Heart Association Class III and IV CHF.Interventions: Subjects were randomized into 2 groups and told to maintain their normal medication and activity regimens. One group then began a 3-times-a-week, 4-week sauna bathing program at 60 +/- 1 degrees C while the other continued with their usual activities and medications. Assignments were then reversed. Sessions were 15 minutes in length but were prolonged an additional 5 minutes for oral temperature increases less than 1.0 degrees C.Main Outcome Measures: Patient acceptance, Minnesota Living With Heart Failure Questionnaire (MLWHFQ) scores; treadmill exercise duration and plasma adrenaline, noradrenalin, aldosterone, atrial naturectic factor, adrenomedulin, and endothelin.Results: Sauna bathing was well tolerated and no adverse effects were reported. Improvements in MLWHFQ scores and treadmill endurance did not achieve statistical significance on a between-group basis but were more marked after the sauna than during the control phase. Neuroendocrine concentrations showed no clear effect of sauna treatment with a between-group statistically significant difference (P=.049) found only in the case of noradrenalin's 24% decrease.Conclusions: Sauna bathing under the moderate and supervised conditions of this study appears to be well tolerated and may be safe for people with CHF. More research is needed to further evaluate the safety and potential benefits of this approach.