Community Trial of a Faith-Based Lifestyle Intervention to Prevent Diabetes Among African-Americans.
Community Trial of a Faith-Based Lifestyle Intervention to Prevent Diabetes Among African-Americans.
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基于信仰的生活方式干预措施的社区试验，以防止非裔美国人之间的糖尿病。
DOI：
10.1007/s10900-015-0071-8
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发表时间：
2016-02
影响因子：
5.9
通讯作者：
Narayan KM
中科院分区：
文献类型：
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作者：
Sattin RW;Williams LB;Dias J;Garvin JT;Marion L;Joshua TV;Kriska A;Kramer MK;Narayan KM
大约 75% 20 岁或以上的非裔美国人 (AA) 体重超标，近 50% 肥胖，但旨在降低 AA 糖尿病风险的社区计划却很少。我们的目标是通过基于信仰的糖尿病预防计划“健康身心”(FBAS) 的调整，从基线到第 12 周和第 12 个月，超重 AA 教区居民的体重和空腹血糖 (FPG) 降低，体力活动 (PA) 增加。我们在 20 个 AA 教会中进行了一项单盲、整群随机、社区试验，招募了 604 名 AA 人，他们年龄在 20 至 64 岁之间，BMI ≥ 25 kg/m2，并且没有糖尿病。教会（及其教区居民）被随机分配接受 FBAS 或健康教育 (HE)。与 HE 参与者相比，FBAS 参与者在 12 周时的调整后体重减轻有显着差异（2.62 kg vs. 0.50 kg，p=0.001），在 12 个月时（2.39 kg vs. -0.465 kg，p=0.005），并且在 12 个月时比 HE 参与者（3%）更有可能（13%）实现 7% 的体重减轻（p<0.001）。 12 周时体重减轻 7%（19% 对比 8%，p<0.001）。两组之间的 FPG 和 PA 没有显着差异。然而，在基线患有糖尿病前期的 15.2% 参与者中，FBAS 组的 FPG 在 12 周时显着下降 (10.93 mg/dl)，而 HE 组增加了 4.22 mg/dl (p=0.017)，并且这些差异在 12 个月时变得更大（FBAS 组减少 12.38 mg/dl；HE 组减少 4.44 mg/dl）增加）（p=0.021）。我们基于信仰的 DPP 调整导致糖尿病前期参与者的总体体重和 FPG 显着减轻。
About 75% of African Americans (AAs) ages 20 or older are overweight and nearly 50% are obese, but community-based programs to reduce diabetes risk in AAs are rare. Our objective was to reduce weight and fasting plasma glucose (FPG) and increase physical activity (PA) from baseline to week-12 and to month-12 among overweight AA parishioners through a faith-based adaptation of the Diabetes Prevention Program called Fit Body and Soul (FBAS). We conducted a single-blinded, cluster randomized, community trial in 20 AA churches enrolling 604 AAs, aged 20 to 64 years with BMI ≥ 25 kg/m2 and without diabetes. The church (and their parishioners) was randomized to FBAS or health education (HE). FBAS participants had a significant difference in adjusted weight loss compared with those in HE (2.62 kg vs. 0.50 kg, p=0.001) at 12-weeks and (2.39 kg vs. −0.465 kg, p=0.005) at 12-months and were more likely (13%) than HE participants (3%) to achieve a 7% weight loss (p<0.001) at 12-weeks and a 7% weight loss (19% vs. 8%, p<0.001) at 12-months. There were no significant differences in FPG and PA between arms. Of the 15.2% of participants with baseline pre-diabetes, those in FBAS had, however, a significant decline in FPG (10.93 mg/dl) at 12-weeks compared with the 4.22 mg/dl increase in HE (p=0.017), and these differences became larger at 12-months (FBAS, 12.38 mg/dl decrease; HE, 4.44 mg/dl increase)(p=0.021). Our faith-based adaptation of the DPP led to a significant reduction in weight overall and in FPG among pre-diabetes participants.