Gastrointestinal Quality of Life Improves Significantly After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass-a Prospective Cross-Sectional Study Within a 2-Year Follow-up
Gastrointestinal Quality of Life Improves Significantly After Sleeve Gastrectomy and Roux-en-Y Gastric Bypass-a Prospective Cross-Sectional Study Within a 2-Year Follow-up
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DOI：
10.1007/s11695-016-2464-x
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发表时间：
2017-05-01
期刊：
影响因子：
2.9
通讯作者：
Fischer, Lars
中科院分区：
文献类型：
--
作者：
Nickel, Felix;Schmidt, Lukas;Fischer, Lars
与一般人群相比，病态肥胖患者的生活质量（QOL）较低。到目前为止，还没有研究比较袖状胃切除术（SG）和Roux-en-Y胃旁路术（RYGB）后胃肠道生活质量的性别和手术差异。减肥手术前后的患者完成了胃肠道生活质量指数（GIQLI），一个36项问卷，有5个分项评分。186名患者完成了问卷调查，其中75名在术前，56名在术后6个月内，55名在术后24个月内。术后24个月内GIQLI总分和所有分项评分均显著改善（80.9 +/- 19.2 vs. 109.2 +/- 17.7，p < 0.001）。胃肠道的具体项目“饱腹感”、“进食愉快”、“进食速度缓慢”和“腹泻”在术后也明显改善，而许多其他胃肠道项目没有差异。术后6个月内SG组的总体GIQLI评分显著高于RYGB组，而术后24个月内两者无显著差异。术后24个月内SG组和RYGB组的胃肠道特异性指标及GIQLI总分在女性和男性间差异无统计学意义，但术后24个月内GIQLI总分及各分项评分均高于男性。与RYGB相比，SG后6个月内的总GIQLI评分显著更高，但在术后24个月内无差异。GIQLI总分在男女患者之间无差异。
Morbidly obese patients have lower quality of life (QOL) when compared to the general population. So far, no studies have compared gender and procedural differences in gastrointestinal QOL after sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB).Patients before and after bariatric surgery completed the gastrointestinal quality of life index (GIQLI), a 36-item questionnaire with five subscores. Differences between SG and RYGB were analyzed, as were gender differences.Some 186 patients completed the questionnaire, 75 before surgery, 56 within 6 months, and 55 within 24 months after surgery. Total GIQLI score and all subscores were significantly better within 24 months after surgery (80.9 +/- 19.2 vs. 109.2 +/- 17.7, p < 0.001). The specific gastrointestinal items 'feeling of fullness', 'eating pleasure', 'slow speed of eating', and 'diarrhea' were also significantly better after surgery whereas many other gastrointestinal items were not different. Total GIQLI score was significantly higher for SG than for RYGB within 6 months, while there were no significant differences within 24 months after surgery. There were also no significant differences in specific gastrointestinal items between SG and RYGB within 24 months after surgery and in total GIQLI score between female and male patients.Total GIQLI score and all subscores were higher within 24 months after bariatric surgery. Total GIQLI score was significantly higher after SG when compared to RYGB within 6 months, but not different within 24 months after surgery. There was no difference in total GIQLI score between female and male patients.