Evidence of immune genes in the crinoïd: Antedon bifida evidence of A.bifida Igkappa gene and a FC receptor one
Evidence of immune genes in the crinoïd: Antedon bifida evidence of A.bifida Igkappa gene and a FC receptor one
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海百合中免疫基因的证据:Antedon bifida A.bifida Igkappa 基因和 FC 受体的证据一
DOI:
10.15406/jabb.2018.05.00154
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发表时间:
2018
期刊:
影响因子:
--
通讯作者:
P. Grange
中科院分区:
文献类型:
--
作者:
M. Leclerc;F. Letourneur;D. Davoult;A. Jolly;P. Grange
The general idea that emerged from the experiments, made in our laboratory, was that Echinodermata, as exemplified, by sea star Asterias rubens (Asterids)and by Ophiocomina nigra (Ophuirids), possessed an immune system, able to mount cellular and humoral-specific responses. After stimulation with a foreign antigen:the horse-radish peroxydase(HRP).1,2 Then,these echinodermata produced a primitive antibody, correlated to an Igkappa gene3–5 to a Fab gene,6 a Fc receptor gene.7 But a question desserves to be put: did the ancestral Echinodermata, Antedon bifida, (Crinoïd) possess such genes? It is why, in a first time, we look for IgKappa gene, Fab gene, Fc receptor gene in this crinoïd by the mean of genomic studies.