THE EVOLUTION OF SEX-CHROMOSOMES
THE EVOLUTION OF SEX-CHROMOSOMES
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DOI：
10.1126/science.1998119
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发表时间：
1991-03-01
期刊：
影响因子：
56.9
通讯作者：
CHARLESWORTH, B
中科院分区：
文献类型：
--
作者：
CHARLESWORTH, B
结构不同的性染色体（X和Y）是最常见的遗传性别决定模式，并在许多不同的分类群中独立进化。 的演化路径，其特性可能已经演变的审查。 这些特性包括X和Y在它们的大部分或全部长度上不能重组，Y染色体的大部分遗传惰性，X染色体基因座活性的剂量补偿，以及Y染色体上重复DNA序列的积累。
Structurally distinct sex chromosomes (X and Y) are the most familiar mode of genetic sex determination and have evolved independently in many different taxa. The evolutionary paths by which their characteristic properties may have evolved are reviewed. These properties include the failure of X and Y to recombine through much or all of their length, the genetic inertness of much of the Y chromosome, dosage compensation of the activity of X chromosomal loci, and the accumulation of repeated DNA sequences on the Y chromosome.