Nationwide Rubella Epidemic — Japan, 2013

Nationwide Rubella Epidemic — Japan, 2013
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全国风疹流行——日本,2013 年

DOI:
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发表时间:
2013
期刊:
MMWR. Morbidity and mortality weekly report
影响因子:
--
通讯作者:
Rebecca Martin
Rebecca Martin
中科院分区:
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文献类型:
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作者:
K. Tanaka;H. Satoh;S. Arai;T. Yamagishi;Y. Yahata;K. Nakashima;T. Sugawara;Y. Ohkusa;T. Matsui;Takehito Saito;Kazuhiko Kanou;T. Shimada;H. Kinoshita;K. Yamashita;Y. Yasui;Y. Tada;Y. Mori;M. Takeda;T. Sunagawa;K. Oishi;P. Strebel;W. Schluter;H. Kamiya;S. Reef;S. Chu;Rebecca Martin

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风疹通常是儿童和成人的一种轻度发热性皮疹疾病;然而,妊娠早期感染,特别是在前16周期间,可能导致流产,死产或出生缺陷的婴儿(即,先天性风疹综合征[CRS])。截至2013年,世界卫生组织的两个区域(美洲区域到2010年和欧洲区域到2015年)已经确定了消灭风疹的目标,西太平洋区域(WPR)已经确定了加速风疹控制和CRS预防的目标。1976年,日本在其国家免疫计划中引入了单一抗原风疹疫苗,目标是初中女生。1989年,针对12-72个月的儿童推出了麻疹-腮腺炎-风疹(MMR)疫苗。然而,成年男性仍然容易感染风疹。2013年1月1日至5月1日,日本风疹监测系统共报告了5,442例风疹病例,其中大多数(77%)病例发生在成年男性中。2012年10月至2013年5月1日期间报告了10例CRS婴儿。制定加速控制或消灭风疹目标的国家和地区应审查其以前和目前的免疫政策和战略,以确定和接种易感人群,并确保所有人群(包括男性和女性)的高人群免疫力。
Rubella usually is a mild, febrile rash illness in children and adults; however, infection early in pregnancy, particularly during the first 16 weeks, can result in miscarriage, stillbirth, or an infant born with birth defects (i.e., congenital rubella syndrome [CRS]). As of 2013, goals to eliminate rubella have been established in two World Health Organization regions (the Region of the Americas by 2010 and the European Region by 2015), and targets for accelerated rubella control and CRS prevention have been established by the Western Pacific Region (WPR). In 1976, Japan introduced single-antigen rubella vaccine in its national immunization program, targeting girls in junior high school. In 1989, a measles-mumps-rubella (MMR) vaccine was introduced, targeting children aged 12-72 months. However, adult males remain susceptible to rubella. From January 1 to May 1, 2013, a total of 5,442 rubella cases were reported through the rubella surveillance system in Japan, with the majority (77%) of cases occurring among adult males. Ten infants with CRS were reported during October 2012-May 1, 2013. Countries and regions establishing a goal of accelerated control or elimination of rubella should review their previous and current immunization policies and strategies to identify and vaccinate susceptible persons and to ensure high population immunity in all cohorts, both male and female.
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